Evidence map›Paper›PMID 26447128›Full record

ReviewGenetics2015

An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System.

Charles S Hoffman, Valerie Wood, Peter A Fantes

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 132 papers.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 234 citations in OpenAlex.

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  7. Establishing MS2-MCP-based single-molecule RNA visualization inbioRxiv : the preprint server for biology · 2026
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  11. Localization and function of septins are susceptible to epitope tagging.bioRxiv : the preprint server for biology · 2025
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72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Charles S HoffmanBiology Department, Boston College, Chestnut Hill, Massachusetts 02467 hoffmacs@bc.edu.ORCID http://orcid.org/0000-0001-8700-1863
Valerie WoodCambridge Systems Biology Centre and Department of Biochemistry, University of Cambridge, CB2 1GA Cambridge, United Kingdom.ORCID http://orcid.org/0000-0001-6330-7526
Peter A FantesSchool of Biological Sciences, College of Science and Engineering, University of Edinburgh EH9 3JR Edinburgh, United Kingdom.
Boston College · USUniversity of Cambridge · GB

Funding

Wellcome Trust 104967
6 · The paper itself

Abstract

The fission yeast Schizosaccharomyces pombe is an important model organism for the study of eukaryotic molecular and cellular biology. Studies of S. pombe, together with studies of its distant cousin, Saccharomyces cerevisiae, have led to the discovery of genes involved in fundamental mechanisms of transcription, translation, DNA replication, cell cycle control, and signal transduction, to name but a few processes. However, since the divergence of the two species approximately 350 million years ago, S. pombe appears to have evolved less rapidly than S. cerevisiae so that it retains more characteristics of the common ancient yeast ancestor, causing it to share more features with metazoan cells. This Primer introduces S. pombe by describing the yeast itself, providing a brief description of the origins of fission yeast research, and illustrating some genetic and bioinformatics tools used to study protein function in fission yeast. In addition, a section on some key differences between S. pombe and S. cerevisiae is included for readers with some familiarity with budding yeast research but who may have an interest in developing research projects using S. pombe.

Indexed as

Chromosomes, FungalDNA DamageDNA ReplicationGenome, FungalHomologous RecombinationLife Cycle StagesModels, GeneticResearchSchizosaccharomyceseducationfission yeastforward geneticsgenetic screenModel Organism Databasemodel systemPrimerSaccharomyces cerevisiaeSchizosaccharomyces pombe

Identifiers

PMID26447128
PMCPMC4596657
OpenAlexW2156503806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.