Evidence map›Paper›PMID 26446894›Full record

SynthesisSports medicine (Auckland, N.Z.)2016

Depression Symptom Severity and Cardiorespiratory Fitness in Healthy and Depressed Adults: A Systematic Review and Meta-Analysis.

Theodoros Papasavvas, Robert O Bonow, Mohammad Alhashemi, Dominic Micklewright

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  4. The Effect of Muscular Strength on Depression Symptoms in Adults: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020
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  8. Sex as a moderator of the association between cardiorespiratory fitness and depressive symptoms in older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Theodoros PapasavvasCardiac Rehabilitation Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar. tpapasavvas@hamad.qa.
Robert O BonowDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Mohammad AlhashemiCardiac Rehabilitation Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Dominic MicklewrightSchool of Biological Sciences, University of Essex, Colchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression symptom severity and cardiorespiratory fitness (CRF) are significant predictors of mortality and disability. However, the relationship between the two is unclear.

objectiveThis meta-analysis assessed the relationship between depression symptom severity and CRF in healthy and depressed adults (aged 18 years and over). SEARCH

methodsThe PubMed, Cochrane Library, Google Scholar and ProQuest databases were browsed for relevant English-language studies published from January 2000 to August 2014. SELECTION CRITERIA: Studies reporting a correlation between a depression scale and maximum oxygen consumption (VO2peak), as well as studies from the data of which such a correlation could be calculated, were included in this analysis. DATA ANALYSIS: Correlation coefficients (CCs) were converted to Fisher's z values, and the analysis was performed using a random-effects model. Then, summary effects and 95% confidence intervals (CIs) were converted back to CCs.

resultsSixteen studies (totalling 4039 participants) were included in this analysis. A modest correlation between depression symptom severity and CRF was found (CC -0.16, 95% CI -0.21 to -0.10), appearing stronger in male participants (CC - 0.22, 95% CI -0.26 to -0.18) than in female participants (CC -0.12, 95% CI -0.19 to -0.05; p = 0.01). There was no difference in the summary effect between healthy and depressed adults (p = 0.43). Heterogeneity was moderate (I2 = 33%; p = 0.09).

conclusionsDepression symptom severity is inversely correlated with CRF, and this correlation is stronger in men than in women. Clinical and prognostic implications of the correlation are discussed. These findings should stimulate further research on the effects of treating one variable on the other.

Indexed as

Cardiorespiratory FitnessAdultDepressionFemaleHumansMajor Depressive DisorderMaleOxygen ConsumptionPublication Bias

Identifiers

PMID26446894

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.