Evidence map›Paper›PMID 26446604›Full record

ReviewJournal of virology2016

Crawling with Virus: Translational Insights from a Neonatal Mouse Model on the Pathogenesis of Respiratory Syncytial Virus in Infants.

Dahui You, Jordy Saravia, David Siefker, Bishwas Shrestha, Stephania A Cormier

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of virology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms ofInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dahui YouDepartment of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Jordy SaraviaDepartment of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
David SiefkerDepartment of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Bishwas ShresthaDepartment of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Stephania A CormierDepartment of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA scormier@uthsc.edu.

Funding

Role of microbiota in increased influenza severity due to particulate matter exposureP42ES013648 · NIEHS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI LOMNICKI, SLAWO M · 2009 to 2024
$27.6M
The Role of IL4R Alpha in Neonatal RSV ImmunopathologyR01AI090059 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI CORMIER, STEPHANIA A · 2011 to 2025
$6.7M
Combustion Generated PM0.1 and Predisposition to AsthmaR01ES015050 · NIEHS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI CORMIER, STEPHANIA A · 2006 to 2022
$4.6M
NIAID NIH HHS R01AI090059NIEHS NIH HHS P42ES013648NIEHS NIH HHS R01ES015050
6 · The paper itself

Abstract

The infant immune response to respiratory syncytial virus (RSV) remains incompletely understood. Here we review the use of a neonatal mouse model of RSV infection to mimic severe infection in human infants. We describe numerous age-specific responses, organized by cell type, observed in RSV-infected neonatal mice and draw comparisons (when possible) to human infants.

Indexed as

Disease Models, AnimalHost-Pathogen InteractionsAnimalsAnimals, NewbornHumansMiceRespiratory Syncytial VirusesRespiratory Syncytial Virus Infections

Identifiers

PMID26446604
PMCPMC4702544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.