ReviewEvoDevo2015
Evolution of the notochord.
Review in EvoDevo, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- The ion channel Anoctamin 10/TMEM16K coordinates organ morphogenesis across scales in the urochordate notochord.PLoS biology · 2024Article
- An amphioxus neurula stage cell atlas supports a complex scenario for the emergence of vertebrate head mesoderm.Nature communications · 2024Article
- Article
- Reaping the benefits of liquid handlers for high-throughput gene expression profiling in a marine model invertebrate.BMC biotechnology · 2024Article
- Gene expression in notochord and nuclei pulposi: a study of gene families across the chordate phylum.BMC ecology and evolution · 2023Article
- Nitric Oxide Function and Nitric Oxide Synthase Evolution in Aquatic Chordates.International journal of molecular sciences · 2023Review
- Rebuilding ships while at sea-Character individuality, homology, and evolutionary innovation.Journal of morphology · 2023Article
- Functions of the FGF signalling pathway in cephalochordates provide insight into the evolution of the prechordal plate.Development (Cambridge, England) · 2022Article
- Single-cell morphometrics reveals ancestral principles of notochord development.Development (Cambridge, England) · 2021Article
- Human umbilical cord-derived mesenchymal stem cells and their chondroprogenitor derivatives reduced pain and inflammation signaling and promote regeneration in a rat intervertebral disc degeneration model.Molecular and cellular biochemistry · 2021Article
- Evolution of Somite Compartmentalization: A View FromFrontiers in cell and developmental biology · 2021Article
- Article
- Key Steps in the Evolution of Mammalian Movement: A Prolegomenal Essay.Neuroscience · 2020Review
- Synchrotron microtomography applied to the volumetric analysis of internal structures of Thoropa miliaris tadpoles.Scientific reports · 2020Article
- A single-cell analysis of the molecular lineage of chordate embryogenesis.Science advances · 2020Article
- Article
- The EJC component Magoh in non-vertebrate chordates.Development genes and evolution · 2020Article
- Article
- The notochord gene regulatory network in chordate evolution: Conservation and divergence from Ciona to vertebrates.Current topics in developmental biology · 2020Review
- Beyond Adult Stem Cells: Dedifferentiation as a Unifying Mechanism Underlying Regeneration in Invertebrate Deuterostomes.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A notochord is characteristic of developing chordates (which comprise amphioxus, tunicates and vertebrates), and, more arguably, is also found in some other animals. Although notochords have been well reviewed from a developmental genetic point of view, there has heretofore been no adequate survey of the dozen or so scenarios accounting for their evolutionary origin. Advances in molecular phylogenetics and developmental genetics have, on the one hand, failed to support many of these ideas (although, it is not impossible that some of these rejects may yet, at least in part, return to favor). On the other hand, current molecular approaches have actually stimulated the revival of two of the old proposals: first that the notochord is a novelty that arose in the chordates, and second that it is derived from a homologous structure, the axochord, that was present in annelid-like ancestors. In the long term, choosing whether the notochord is a chordate novelty or a legacy from an ancient annelid (or perhaps an evolutionary derivative from precursors yet to be proposed) will probably require descriptions of gene regulatory networks involved in the development of notochords and notochord-like structures in a wide spectrum of animals. For now, one-way forward will be studies of all aspects of the biology of enteropneust hemichordates, a group widely thought to be the key to understanding the evolutionary origin of the chordates.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.