Evidence map›Paper›PMID 26446319›Full record

ArticleBMJ case reports2015

Phaeochromocytoma with hypercortisolism and hypercalcaemia.

Ovie Edafe, Jonathan Webster, Malee Fernando, Ragu Vinayagam, Sabapathy P Balasubramanian

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Bilateral adrenal uptake ofScientific reports · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ovie EdafeSheffield Teaching Hospitals, Sheffield, UK.
Jonathan WebsterDepartment of Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK.
Malee FernandoDepartment of Histopathology, Sheffield Teaching Hospitals, Sheffield, UK.
Ragu VinayagamDepartment of Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Sabapathy P BalasubramanianDepartment of Surgical Oncology, University of Sheffield, Sheffield, UK.
Sheffield Teaching Hospitals NHS Foundation Trust · GBUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of phaeochromocytoma associated with hypercortisolism and hypercalcaemia in a 62-year-old man. The patient presented to clinic, with a 3-year history of exertional headaches, and a 4-month history of increasing fatigue, sweating and palpitations, loss of appetite and weight, and sleepiness. He did not have a medical, family or social history that could account for these symptoms. 24 h urinary catecholamines, plasma metanephrines, 24 h urinary cortisol and adjusted serum calcium, were elevated. Overnight low-dose dexamethasone suppression test did not suppress morning plasma cortisol. Serum intact parathyroid hormone and parathyroid hormone-related peptide were low, and adrenocorticotropic hormone was normal. The patient was treated with intravenous 0.9% sodium chloride and disodium pamidronate to control hypercalcaemia. CT showed a 10 cm left adrenal mass. Following inpatient treatment with phenoxybenzamine, he underwent a left adrenectomy and histology confirmed a phaeochromocytoma. Postoperatively, he required long-term steroids for contralateral adrenal suppression. Adjusted serum calcium returned to normal postoperatively.

Indexed as

Adrenal Gland NeoplasmsCalciumFollow-Up StudiesHumansHydrocortisoneHypercalcemiaMaleMiddle AgedPheochromocytomaCalciumHydrocortisone

Identifiers

PMID26446319
PMCPMC4600802
OpenAlexW2302615919

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.