ArticleMaternal & child nutrition2016
Lower levels of human milk adiponectin predict offspring weight for age: a study in a lean population of Filipinos.
Article in Maternal & child nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Human Milk Bioactive Components and Child Growth and Body Composition in the First 2 Years: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- Adolescent mothers' body composition and metabolic hormones (adiponectin, ghrelin, and leptin) in blood and human milk: associations with infant body composition.European journal of clinical nutrition · 2026Article
- High-intensity exercise increases breast milk adiponectin concentrations: a randomised cross-over study.Frontiers in nutrition · 2023Article
- Human Milk Metabolic Hormones: Analytical Methods and Current Understanding.International journal of molecular sciences · 2021Review
- Importance of Bioactive Substances in Sheep's Milk in Human Health.International journal of molecular sciences · 2021Review
- Diversity and temporal dynamics of primate milk microbiomes.American journal of primatology · 2019Article
- Adiponectin and Cardiovascular Risk. From Pathophysiology to Clinic: Focus on Children and Adolescents.International journal of molecular sciences · 2019Review
- Human Milk Adiponectin and Leptin and Infant Body Composition over the First 12 Months of Lactation.Nutrients · 2018Article
- [Association of leptin, adiponectin, and ghrelin in breast milk with the growth of infants with exclusive breastfeeding].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
- The Mother-Infant Study Cohort (MISC): Methodology, challenges, and baseline characteristics.PloS one · 2018Article
- Associations between Maternal Body Composition and Appetite Hormones and Macronutrients in Human Milk.Nutrients · 2017Article
- Lower levels of human milk adiponectin predict offspring weight for age: a study in a lean population of Filipinos.Maternal & child nutrition · 2016Article
- Bioactive factors in milk across lactation: Maternal effects and influence on infant growth in rhesus macaques (Macaca mulatta).American journal of primatology · 2016Article
- A narrative review of the associations between six bioactive components in breast milk and infant adiposity.Obesity (Silver Spring, Md.) · 2016Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prior studies have reported a significant, inverse association between adiponectin in human milk and offspring growth velocity. Less is known about this association in populations characterised by a loss of weight for age z-scores (WAZs) in early life. We investigated the association between maternal body composition and milk adiponectin in a sample of Filipino mothers. We then tested for an association between milk adiponectin and size for age in their infants. A total of 117 Filipino mothers nursing infants from 0 to 24 months were recruited from Cebu, Philippines. Anthropometrics, interviews and milk samples were collected and analysed using standard protocols. Mean milk adiponectin in this sample was 7.47 ± 5.75 ng mL(-1) . Mean infant WAZ and weight for length (WLZ) decreased with age. Maternal body composition was not associated with milk adiponectin content. Milk adiponectin had a significant, positive association with infant WAZ and WLZ. Prior reports have found an inverse association between milk adiponectin and infant WAZ. Here, we report that in lean populations with lower milk adiponectin, there is a positive association with infant WAZ, possibly reflecting pleiotropic biological functions of adiponectin for post-natal growth. This study increases the understanding of normal biological variation in milk adiponectin and the consequences of low levels of milk adiponectin for offspring growth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.