Evidence map›Paper›PMID 26446073›Full record

ArticleTranslational stroke research2015

Microglia/Macrophage Polarization After Experimental Intracerebral Hemorrhage.

Hao Zhao, Thomas Garton, Richard F Keep, Ya Hua, Guohua Xi

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational stroke research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04088630 (Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage), which is not on this map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04088630 early_phase1completednot on this mapstarted 2020, after this paper: background citation

Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage

TypeinterventionalSponsorWake Forest University Health SciencesRan2020 to 2024Enrolled28ConditionsIntracerebral Hemorrhage, Cerebral Edema, Stroke Hemorrhagic, Intracerebral Hemorrhage, HypertensiveArmsFingolimod, Placebo, Open-label Fingolimod
3 · Its place in the literature

Who cites it

76 citing papers in PubMed.

  1. Article
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  19. Review
  20. From the immune system to mood disorders especially induced byFrontiers in cellular and infection microbiology · 2023
    Review

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao ZhaoDepartment of Neurosurgery, University of Michigan, R5018 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA.
Thomas GartonDepartment of Neurosurgery, University of Michigan, R5018 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA.
Richard F KeepDepartment of Neurosurgery, University of Michigan, R5018 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA.
Ya HuaDepartment of Neurosurgery, University of Michigan, R5018 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA.
Guohua XiDepartment of Neurosurgery, University of Michigan, R5018 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA. guohuaxi@umich.edu.

Funding

Iron, minocycline and brain injury after intracerebral hemorrhageR01NS090925 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XI, GUOHUA · 2015 to 2019
$1.7M
Mechanisms of Brain Injury after Intraventricular HemorrhageR01NS073595 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XI, GUOHUA · 2012 to 2016
$1.7M
Mechanisms of early brain injury after subarachnoid hemmorrhageR01NS079157 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XI, GUOHUA · 2012 to 2016
$1.7M
Lipocalin-2 and Intracerebral Hemorrhage-induced Brain InjuryR21NS091545 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUA, YA · 2015 to 2016
$427k
CD47 and hematoma clearance in intracerebral hemorrhageR21NS084049 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUA, YA · 2013 to 2014
$425k
NINDS NIH HHS NS-073595NINDS NIH HHS NS-079157NINDS NIH HHS NS-084049NINDS NIH HHS NS-090925NINDS NIH HHS NS-091545NINDS NIH HHS R01 NS073595NINDS NIH HHS R01 NS079157NINDS NIH HHS R01 NS090925NINDS NIH HHS R21 NS084049NINDS NIH HHS R21 NS091545
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell PolarityAnimalsCerebral HemorrhageHumansMacrophagesMicroglia

Identifiers

PMID26446073
PMCPMC4628553

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.