Evidence map›Paper›PMID 26446052›Full record

ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2015

Gender differences in right ventricular function in patients with non-ischaemic cardiomyopathy.

M Martínez-Sellés, E Pérez-David, R Yotti, J Jiménez-Borreguero, G Loughlin, L Gallego, A Ayesta, M J Olivera, J Bermejo, F Fernández-Avilés

Open access · diamondAbstract read
In one paragraph

Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. New Insights in RBM20 Cardiomyopathy.Current heart failure reports · 2020
    Review
  4. Sex Influence on Heart Failure Prognosis.Frontiers in cardiovascular medicine · 2020
    Review
  5. Right ventricular function in dilated cardiomyopathy: women are the stronger sex!Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2015
    Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

M Martínez-SellésCardiology Department, Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, and Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense de Madrid, and Universidad Europea de Madrid, Calle Dr. Esquerdo 46, 28007, Madrid, Spain. mmselles@secardiologia.es.
E Pérez-DavidCardiology Department, Hospital General Universitario Gregorio Marañón, and Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
R YottiCardiology Department, Hospital General Universitario Gregorio Marañón, and Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
J Jiménez-BorregueroRadiology and Cardiology Departments, Hospital Universitario de la Princesa, Madrid, Spain.
G LoughlinCardiology Department, Hospital General Universitario Gregorio Marañón, and Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
L GallegoCardiology Department, Hospital General Universitario Gregorio Marañón, and Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
A AyestaCardiology Department, Hospital General Universitario Gregorio Marañón, and Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
M J OliveraRadiology and Cardiology Departments, Hospital Universitario de la Princesa, Madrid, Spain.
J BermejoCardiology Department, Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, and Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense de Madrid, and Universidad Europea de Madrid, Calle Dr. Esquerdo 46, 28007, Madrid, Spain.
F Fernández-AvilésCardiology Department, Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, and Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense de Madrid, and Universidad Europea de Madrid, Calle Dr. Esquerdo 46, 28007, Madrid, Spain.
Hospital General Universitario Gregorio Marañón · ESHospital Universitario de La Princesa · ESUniversidad Europea de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate sex-related differences in right ventricular (RV) function, assessed with cardiac magnetic resonance imaging, in patients with stable non-ischaemic dilated cardiomyopathy.

methodsProspective multicentre study. We included 71 patients (38 men) and 14 healthy volunteers.

resultsMean age was 60.9 ± 12.2 years. Men presented higher levels of haemoglobin and white blood cell counts than women, and performed better in cardiopulmonary stress testing. A total of 24 patients (12 women) presented severe left ventricular (LV) systolic dysfunction, 32 (13 female) moderate and 15 (8 women) mild LV systolic dysfunction. In the group with severe LV systolic dysfunction, average right ventricular ejection fraction (RVEF) was normal in women (52 ± 4 %), whereas it was reduced in men (39 ± 3 %) p = 0.035. Only one woman (8 %) had severe RV systolic dysfunction (RVEF < 35 %) compared with 6 men (50 %) p < 0.001. In patients with moderate and mild LV dysfunction , the mean RVEF was normal in both men and women. In the 14 healthy volunteers, the lowest value of RVEF was 48 % and mean RVEF was normal in women (56 ± 2 %) and in men (51 ±  1 %), p = 0.08.

conclusionsIn patients with dilated cardiomyopathy, RV systolic dysfunction is found mainly in male patients with severe LV systolic dysfunction.

Indexed as

Dilated cardiomyopathyGenderHeart failureRight ventricleSex

Identifiers

PMID26446052
PMCPMC4651963
OpenAlexW2173890704

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.