ArticleTherapeutic advances in endocrinology and metabolism2015
Effect of Ramadan fasting in Saudi Arabia on serum bone profile and immunoglobulins.
Article in Therapeutic advances in endocrinology and metabolism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Pooled it
- Determinants of Serum Immunoglobulin Levels: A Systematic Review and Meta-Analysis.Frontiers in immunology · 2021Pooled it
- Time-Restricted Eating for 12 Weeks Does Not Adversely Alter Bone Turnover in Overweight Adults.Nutrients · 2021Trial
- 24-Hour Ambulatory Blood Pressure Monitoring during Ramadan Fasting: A Three-Year Cross-Sectional Study From a Tertiary Medical Center in Turkey.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Challenges in the Pediatric Celiac Disease Diagnosis: An Up-to-Date Review.Diagnostics (Basel, Switzerland) · 2025Review
- Dietary recommendations of the Moroccan Society of Rheumatology (SMR) for patients with ostéosarcopenia.Archives of osteoporosis · 2024Review
- The Effects of Different Dietary Patterns on Bone Health.Nutrients · 2024Review
- The current insights of mitochondrial hormesis in the occurrence and treatment of bone and cartilage degeneration.Biological research · 2024Review
- Review
- A case report of primary hyperparathyroidism in an adolescent during Ramadan fast.SAGE open medical case reports · 2024Article
- Ramadan fasting and exercise combination therapy: A novel approach for osteoporosis prevention in ovariectomized rats.Frontiers in physiology · 2024Article
- The effect of Ramadan intermittent fasting on anthropometric, hormonal, metabolic, inflammatory, and oxidative stress markers in pre-and post-menopausal women: a prospective cohort of Saudi women.Frontiers in nutrition · 2024Article
- Elevated Total Serum Immunoglobulin A Levels in Patients with Suspicion for Celiac Disease.Journal of clinical medicine · 2023Article
- Article
- Effect of Intermittent Fasting on Glucose Homeostasis and Bone Remodeling in Glucocorticoid-Induced Osteoporosis Rat Model.Journal of bone metabolism · 2021Article
- The potential effect of Ramadan fasting on musculoskeletal diseases: new perspectives.Clinical rheumatology · 2021Review
- The significant effect on musculoskeletal metabolism and bone density of the Eastern Mediterranean Christian Orthodox Church fasting.European journal of clinical nutrition · 2020Article
- Fasting Ramadan During COVID-19 Pandemic: Immunomodulatory Effect.Frontiers in nutrition · 2020Article
- Cortical thickness, neurocognitive, and body composition effects of fasting during Ramadan.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Article
- Stress, Glucocorticoids and Bone: A Review From Mammals and Fish.Frontiers in endocrinology · 2018Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEach year Muslims fast from dawn to sunset for 1 month (Ramadan). In Saudi Arabia, the sleep-wake cycle during Ramadan is severely disturbed and is associated with abolition of the circadian cortisol rhythm, exposing Saudis to continuously increased cortisol levels, which may influence the immune response. In addition to cortisol, sleep and fasting affect the secretion of parathyroid hormone (PTH) and hence bone metabolism.
methodsOur objective was to investigate the effect of Ramadan type fasting on secretory patterns of PTH, markers of bone metabolism, and serum immunoglobulins. Blood samples from healthy young volunteers were collected at 9 a.m. and 9 p.m. (± 1 hour) before (Shaban) and 2 weeks into Ramadan. Calcium, phosphorus, magnesium, albumin, alkaline phosphatase, 25-OH vitamin D, intact PTH (iPTH), and immunoglobulin (Ig) A, M and G were measured.
resultsDuring Ramadan, evening-adjusted calcium was higher (p = 0.036) and phosphate lower (p < 0.001) than the corresponding morning value. Moreover, the Ramadan mean morning phosphate was higher and the evening level lower was than Shabaan values (p = 0.010 and p <0.001, respectively), while mean iPTH level was decreased compared with the morning value (p = 0.001), and the evening mean during Shabaan (p = 0.029). Mean IgG concentration was significantly lower during Ramadan (p = 0.003 and p = 0.021 for morning and evening, respectively).
conclusionsChanges in dietary practices during Ramadan modulated PTH secretion to a pattern which might be beneficial to bone health. Combined effects of fasting and disturbed sleep led to a noted decrease in IgG level. Therefore, a possible beneficial effect of fasting on bone turnover is combined with decreased immune response.
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