ArticleInternational journal of preventive medicine2015
Effects of Probiotics on Biomarkers of Oxidative Stress and Inflammatory Factors in Petrochemical Workers: A Randomized, Double-blind, Placebo-controlled Trial.
Article in International journal of preventive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Probiotic intake and mental health in healthy working adults: a systematic review and meta-analysis of randomized controlled trials.BMC psychology · 2026Pooled it
- The Effects of Supplementation with Probiotic on Biomarkers of Oxidative Stress in Adult Subjects: a Systematic Review and Meta-analysis of Randomized Trials.Probiotics and antimicrobial proteins · 2020Pooled it
- Prebiotics, Prosynbiotics and Synbiotics: Can They Reduce Plasma Oxidative Stress Parameters? A Systematic Review.Probiotics and antimicrobial proteins · 2017Pooled it
- Next-generation microbiome therapeutics: psychobiotics and fecal microbiota transplants for mental health treatment.Frontiers in cellular and infection microbiology · 2026Review
- The Pediatric Microbiota-Gut-Brain Axis: Implications for Neuropsychiatric Development and Intervention.Children (Basel, Switzerland) · 2025Review
- Yogurt Supplementation Can Ameliorate Fatty Liver Diseases and Metabolic Syndrome in High Fat-Induced Conditions in Mice.Food science & nutrition · 2025Article
- Advanced Membrane Simulations in Probiotics and Gut Microbiome Interaction Research: The Current Trends and Insights.Current pharmaceutical design · 2025Review
- The preventive effects ofHeliyon · 2024Article
- Probiotic Improves Skin Oxidation, Elasticity, and Structural Properties in Aging Rats.Preventive nutrition and food science · 2023Article
- The effect of synbiotic supplementation on atherogenic indices, hs-CRP, and malondialdehyde, as major CVD-related parameters, in women with gestational diabetes mellitus: a secondary data-analysis of a randomized double-blind, placebo-controlled study.Diabetology & metabolic syndrome · 2022Article
- The Antioxidant Activity ofAntioxidants (Basel, Switzerland) · 2022Article
- Hibiscus sabdariffa extract improves hepatic steatosis, partially through IRS-1/Akt and Nrf2 signaling pathways in rats fed a high fat diet.Scientific reports · 2022Article
- Astaxanthin FromFrontiers in nutrition · 2022Article
- Microbiome-Metabolomics Reveals Endogenous Alterations of Energy Metabolism by the Dushen Tang to Attenuate D-Galactose-Induced Memory Impairment in Rats.BioMed research international · 2021Article
- Delaying memory decline: different options and emerging solutions.Translational psychiatry · 2020Review
- High-fat diet-induced metabolic syndrome and oxidative stress in obese rats are ameliorated by yogurt supplementation.Scientific reports · 2019Article
- Improvement of Redox State and Functions of Immune Cells as Well as of Behavioral Response in Aged Mice After Two-Week Supplementation of Fermented Milk with Probiotics.Current microbiology · 2019Article
- The Possibility of an Infectious Etiology of Alzheimer Disease.Molecular neurobiology · 2019Review
- Lactobacillus rhamnosus GG increases cyclooxygenase-2 expression and prostaglandin E2 secretion in colonic myofibroblasts via a MyD88-dependent mechanism during homeostasis.Cellular microbiology · 2018Article
- The Microbiota-Inflammasome Hypothesis of Major Depression.BioEssays : news and reviews in molecular, cellular and developmental biology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the current study was to determine effects of probiotic yoghurt and multispecies probiotic capsule supplementation on biomarkers of oxidative stress and inflammatory factors in petrochemical workers.
methodsThis randomized, double-blind, placebo-controlled trial was done among petrochemical workers. Subjects were randomly divided into three groups to receive 100 g/day probiotic yogurt (n = 12) or one probiotic capsule daily (n = 13) or 100 g/day conventional yogurt (n = 10) for 6 weeks. The probiotic yoghurt was containing two strains of Lactobacillus acidophilus and Bifidobacterium lactis with a total of min 1 × 10(7) CFU. Multispecies probiotic capsule contains seven probiotic bacteria spices Actobacillus casei 3 × 10(3), L. acidophilus 3 × 10(7), Lactobacillus rhamnosus 7 × 10(9), Lactobacillus bulgaricus 5 × 10(8), Bifidobacterium breve 2 × 10(10), Bifidobacterium longum 1 × 10(9) and Streptococcus thermophilus 3 × 10(8) CFU/g. Fasting blood samples were obtained at the beginning and end of the trial to quantify biomarkers of oxidative stress and inflammatory factors.
resultsAlthough a significant within-group decrease in plasma protein carbonyl levels was seen in the probiotic capsule group (326.0 ± 308.9 vs. 251.0 ± 176.3 ng/mL, P = 0.02), the changes were similar among the three groups. In addition, significant within-group decreases in plasma iso prostaglandin were observed in the probiotic supplements group (111.9 ± 85.4 vs. 88.0 ± 71.0 pg/mL, P = 0.003) and in the probiotic yogurt group (116.3 ± 93.0 vs. 92.0 ± 66.0 pg/mL, P = 0.02), nevertheless there were no significant change among the three groups.
conclusionsTaken together, consumption of probiotic yogurt or multispecies probiotic capsule had beneficial effects on biomarkers of oxidative stress in petrochemical workers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.