ArticlePloS one2015
Comparative Transcriptome Analysis Reveals Cool Virulence Factors of Ralstonia solanacearum Race 3 Biovar 2.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 56 citations in OpenAlex.
- Analysis of Bacterial Wilt Management Strategies From the Dynamic Perspective of Environmental Adaptation Approaches of Ralstonia solanacearum.Environmental microbiology reports · 2026Review
- Contribution of a Novel TetR/AcrR Family Transcriptional Regulator RalT of Ralstonia pseudosolanacearum Strain OE1-1 to the Fine-Tuning of Its Virulence.MicrobiologyOpen · 2026Article
- Lectins and polysaccharide EPS I have flow-responsive roles in the attachment and biofilm mechanics of plant pathogenic Ralstonia.PLoS pathogens · 2024Article
- N-acyl homoserine lactone cell-cell diffusible signalling in the Ralstonia solanacearum species complex.Molecular plant pathology · 2024Review
- Microbiome-Mediated Strategies to Manage Major Soil-Borne Diseases of Tomato.Plants (Basel, Switzerland) · 2024Review
- Interkingdom Signaling of the Insect PathogenMicroorganisms · 2023Article
- Cell Density-Regulated Adhesins Contribute to Early Disease Development and Adhesion in Ralstonia solanacearum.Applied and environmental microbiology · 2023Article
- Biocomputational Assessment of Natural Compounds as a Potent Inhibitor to Quorum Sensors inMolecules (Basel, Switzerland) · 2022Article
- Dynamic expression of Ralstonia solanacearum virulence factors and metabolism-controlling genes during plant infection.BMC genomics · 2021Article
- Every cloud has a silver lining: how abiotic stresses affect gene expression in plant-pathogen interactions.Journal of experimental botany · 2021Review
- Review
- Implication of the Type III Effector RipS1 in the Cool-Virulence ofFrontiers in plant science · 2021Article
- Microbial communities and gene contributions in smokeless tobacco products.Applied microbiology and biotechnology · 2020Article
- Taxonomy and Phylogenetic Research on Ralstonia solanacearum Species Complex: A Complex Pathogen with Extraordinary Economic Consequences.Pathogens (Basel, Switzerland) · 2020Review
- Transcriptome of Pectobacterium carotovorum subsp. carotovorum PccS1 infected in calla plants in vivo highlights a spatiotemporal expression pattern of genes related to virulence, adaptation, and host response.Molecular plant pathology · 2020Article
- Major exopolysaccharide, EPS I, is associated with the feedback loop in the quorum sensing of Ralstonia solanacearum strain OE1-1.Molecular plant pathology · 2019Article
- Contribution of a lectin, LecM, to the quorum sensing signalling pathway of Ralstonia solanacearum strain OE1-1.Molecular plant pathology · 2019Article
- Rhizosphere microbiome structure alters to enable wilt resistance in tomato.Nature biotechnology · 2018Article
- Ralfuranones contribute to mushroom-type biofilm formation by Ralstonia solanacearum strain OE1-1.Molecular plant pathology · 2018Article
- Involvement of ralfuranones in the quorum sensing signalling pathway and virulence of Ralstonia solanacearum strain OE1-1.Molecular plant pathology · 2018Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While most strains of the plant pathogenic bacterium Ralstonia solanacearum are tropical, the race 3 biovar 2 (R3bv2) subgroup attacks plants in cooler climates. To identify mechanisms underlying this trait, we compared the transcriptional profiles of R. solanacearum R3bv2 strain UW551 and tropical strain GMI1000 at 20°C and 28°C, both in culture and during tomato pathogenesis. 4.2% of the ORFs in the UW551 genome and 7.9% of the GMI1000 ORFs were differentially expressed by temperature in planta. The two strains had distinct transcriptional responses to temperature change. GMI1000 up-regulated several stress response genes at 20°C, apparently struggling to cope with plant defenses. At the cooler temperature, R3bv2 strain UW551 up-regulated a cluster encoding a mannose-fucose binding lectin, LecM; a quorum sensing-dependent protein, AidA; and a related hypothetical protein, AidC. The last two genes are absent from the GMI1000 genome. In UW551, all three genes were positively regulated by the adjacent SolI/R quorum sensing system. These temperature-responsive genes were required for full virulence in R3bv2. Mutants lacking lecM, aidA, or aidC were each significantly more reduced in virulence on tomato at 20°C than at 28°C in both a naturalistic soil soak inoculation assay and when they were inoculated directly into tomato stems. The lecM and aidC mutants also survived poorly in potato tubers at the seed tuber storage temperature of 4°C, and the lecM mutant was defective in biofilm formation in vitro. Together, these results suggest novel mechanisms, including a lectin, are involved in the unique temperate epidemiology of R3bv2.
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