ArticleBMC public health2015
Comparison of characteristics and mortality in multidrug resistant (MDR) and non-MDR tuberculosis patients in China.
Article in BMC public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictors of mortality in patients with drug-resistant tuberculosis: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Multidrug resistant tuberculosis (MDR-TB) in Eritrea: a retrospective cohort analysis of mortality and associated factors (2013 - 2023).Frontiers in cellular and infection microbiology · 2026Article
- Time to reoccurrence of tuberculosis and its predictors among adult HIV/AIDS patients on ART at public hospitals in East and Horro Guduru Wollega zones, West Ethiopia: a retrospective cohort study.BMC public health · 2025Article
- Timing and predictors of death during treatment in patients with multidrug/rifampin-resistant tuberculosis in South Korea.The Korean journal of internal medicine · 2024Article
- A systematic review and meta-analysis on the correlation between HIV infection and multidrug-resistance tuberculosis.Heliyon · 2023Article
- The impact of COVID-19 pandemic on reported tuberculosis incidence and mortality in China: An interrupted time series analysis.Journal of global health · 2023Article
- Risk factors for mortality and multidrug resistance in pulmonary tuberculosis in Guatemala: A retrospective analysis of mandatory reporting.Journal of clinical tuberculosis and other mycobacterial diseases · 2021Article
- Outcome Impacts Due to Pathogen-Specific Antimicrobial Resistance: A Narrative Review of Published Literature.International journal of environmental research and public health · 2020Review
- Epidemiological characteristics of pulmonary tuberculosis in Anhui Province, Eastern China from 2013 to 2018.PloS one · 2020Article
- Tuberculosis treatment outcome: The case of women in Ethiopia and China, ten-years retrospective cohort study.PloS one · 2019Observational
- Assessment of the risk factors associated with multidrug-resistant tuberculosis in Sudan: a case-control study.Epidemiology and health · 2019Article
- Molecular screening of multidrug-resistance tuberculosis by a designated public health laboratory in Taiwan.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
- Treatment outcomes of patients with multidrug-resistant and extensively drug resistant tuberculosis in Hunan Province, China.BMC infectious diseases · 2017Article
- Reasons for Non-Enrollment in Treatment among Multi-Drug Resistant Tuberculosis Patients in Hunan Province, China.PloS one · 2017Article
- Impact of Multidrug Resistance on Tuberculosis Recurrence and Long-Term Outcome in China.PloS one · 2017Article
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4 authors.
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Abstract
backgroundWe conducted a cohort study to compare the characteristics of MDR-TB with non-MDR-TB patients and to measure long term (9-year) mortality rate and determine factors associated with death in China.
methodsWe reviewed the medical records of 250 TB cases from a 2001 survey to compare 100 MDR-TB patients with 150 non-MDR-TB patients who were treated in 2001-2002. Baseline attributes extracted from the records were compared between the two cohorts and long-term mortality and risk factors were determined at nine-year follow-up in 2010.
resultsAmong the 234 patients successfully followed up, 63 (26.9%) were female and 171 (73.1 %) were male. MDR-TB patients had poorer socioeconomic status compared to non-MDRTB. Nine years after the diagnosis of TB, 69 or 29.5 % of the 234 patients had died (32 or 21.6 % of non-MDR-TB versus 37 or 43.0 % of MDR-TB) and the overall mortality rate was 39/1000 per year (PY) (27/1000 PY among non-MDR versus 63/1000 PY among MDR-TB). Factors associated with death included: MDR status (hazard ratio (HR): 1.86; CI: 1.09-3.13), limited education of primary school or lower (HR: 2.51; CI 1.34-4.70) and received TB treatment during the nine-year period (HR 1.82; 95 % CI 1.02-3.26).
conclusionsMDR-TB was a strong predictor for poor long-term outcome. High quality diagnosis and treatment must be ensured. Greater reimbursement or free treatment may be needed to provide access for the poor and vulnerable populations, and to increase treatment compliance.
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