ArticleAmerican journal of epidemiology2015
Childhood wheezing, asthma, allergy, atopy, and lung function: different socioeconomic patterns for different phenotypes.
Article in American journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Machine learning-derived asthma and allergy trajectories in children: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Socioeconomic circumstances and respiratory function from childhood to early adulthood: a systematic review and meta-analysis.BMJ open · 2019Pooled it
- Allergies and Childhood Acute Lymphoblastic Leukemia: A Case-Control Study and Meta-analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018Pooled it
- Distinct epidemiological patterns of allergic disease comorbidity across elementary school grades in Taiwan.Pediatric research · 2026Article
- Beyond cigarettes: waterpipe tobacco use as a key driver of paediatric asthma in Jordan.BMJ paediatrics open · 2025Article
- Social inequalities in childhood asthma.The World Allergy Organization journal · 2024Review
- Factors related with lung functions among Orang Asli in Tasik Chini, Malaysia: a cross-sectional study.BMC public health · 2024Article
- Associations between symptoms of attention-deficit hyperactivity disorder, socioeconomic status and asthma in children.Npj mental health research · 2024Article
- Preschool children from lower household incomes experience inequality in asthma treatment: findings from a Danish nationwide cohort study.European journal of public health · 2024Article
- Socioeconomic status and emergency department visits in adults with a history of severe childhood asthma: a register-based study.European clinical respiratory journal · 2024Article
- Health effects associated with exposure to secondhand smoke: a Burden of Proof study.Nature medicine · 2024Article
- Association Between Lung Function of Children and Their Socioeconomic Conditions: A Systematic Review.International journal of general medicine · 2024Review
- Trend and heterogeneity in forced vital capacity among Chinese students during 1985-2019: results from Chinese National Survey on Students' Constitution and Health.Respiratory research · 2023Article
- Clinical features and later prognosis of replicable early-life wheeze clusters from two birth cohorts 12 years apart.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2023Article
- Socioeconomic position, bronchiolitis and asthma in children: counterfactual disparity measures from a national birth cohort study.International journal of epidemiology · 2023Article
- Assessing the prevalence and severity of asthma, rhinitis, and eczema among schoolchildren (6-7 and 13-14 years old) in Khuzestan, Iran: a cross-sectional survey.BMC pediatrics · 2022Article
- The causal association between maternal smoking around birth on childhood asthma: A Mendelian randomization study.Frontiers in public health · 2022Article
- Longitudinal Association of Economic Growth with Lung Function of Chinese Children and Adolescents over 30 Years: Evidence from Seven Successive National Surveys.International journal of environmental research and public health · 2021Article
- Self-Reported Dental Caries by Mexican Elementary and Middle-School Schoolchildren in the Context of Socioeconomic Indicators: A National Ecological Study.Children (Basel, Switzerland) · 2021Article
- Geography, generalisability, and susceptibility in clinical trials.The Lancet. Respiratory medicine · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Identifying preventable exposures that lead to asthma and associated allergies has proved challenging, partly because of the difficulty in differentiating phenotypes that define homogeneous disease groups. Understanding the socioeconomic patterns of disease phenotypes can help distinguish which exposures are preventable. In the present study, we identified disease phenotypes that are susceptible to socioeconomic variation, and we determined which life-course exposures were associated with these inequalities in a contemporary birth cohort. Participants included children from the Avon Longitudinal Study of Parents and Children, a population-based birth cohort in England, who were born in 1991 and 1992 and attended the clinic at 7-8 years of age (n = 6,378). Disease phenotypes included asthma, atopy, wheezing, altered lung function, and bronchial reactivity phenotypes. Combining atopy with a diagnosis of asthma from a doctor captured the greatest socioeconomic variation, including opposing patterns between phenotype groups: Children with a low socioeconomic position (SEP) had more asthma alone (adjusted multinomial odds ratio = 1.50, 95% confidence interval: 1.21, 1.87) but less atopy alone (adjusted multinomial odds ratio = 0.80, 95% confidence interval: 0.66, 0.98) than did children with high SEP. Adjustment for maternal exposure to tobacco smoke during pregnancy and childhood exposure to tobacco smoke reduced the odds of asthma alone in children with a low SEP. Current inequalities among children who have asthma but not atopy can be prevented by eliminating exposure to tobacco smoke. Other disease phenotypes were not socially patterned or had SEP patterns that were not related to smoke exposure.
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