Evidence map›Paper›PMID 26442841›Full record

ReviewTrends in cell biology2016

Diversity Matters: A Revised Guide to Myelination.

Giulio Srubek Tomassy, Lori Bowe Dershowitz, Paola Arlotta

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Wrap it up: myelination of transplanted neurons for repair.Frontiers in cellular neuroscience · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. AGenes · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giulio Srubek TomassyDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: giulio_tomassy@harvard.edu.
Lori Bowe DershowitzDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.
Paola ArlottaDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: paola_arlotta@harvard.edu.

Funding

Projection neuron control over interneuron positioning into neocortical circuitryR01NS078164 · NINDS · HARVARD UNIVERSITY · PI ARLOTTA, PAOLA · 2013 to 2017
$1.8M
NINDS NIH HHS R01 NS078164
6 · The paper itself

Abstract

The evolutionary success of the vertebrate nervous system is largely due to a unique structural feature--the myelin sheath, a fatty envelope that surrounds the axons of neurons. By increasing the speed by which electrical signals travel along axons, myelin facilitates neuronal communication between distant regions of the nervous system. We review the cellular and molecular mechanisms that regulate the development of myelin as well as its homeostasis in adulthood. We discuss how finely tuned neuron-oligodendrocyte interactions are central to myelin formation during development and in the adult, and how these interactions can have profound implications for the plasticity of the adult brain. We also speculate how the functional diversity of both neurons and oligodendrocytes may impact on the myelination process in both health and disease.

Indexed as

AdultAnimalsAxonsBiological EvolutionHumansMyelin SheathNeuronsOligodendrogliaSynaptic Transmissionbrain plasticitycerebral cortexdevelopmentmyelinneuron–glia interactionoligodendrocytes

Identifiers

PMID26442841
PMCPMC4727993

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.