ArticleScientific reports2015
Light attenuates lipid accumulation while enhancing cell proliferation and starch synthesis in the glucose-fed oleaginous microalga Chlorella zofingiensis.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Costs of photosynthesis and cellular remodeling in trophic transitions of the unicellular red alga Galdieria partita.Communications biology · 2025Article
- Artificial Intelligence in Advancing Algal Bioactive Ingredients: Production, Characterization, and Application.Foods (Basel, Switzerland) · 2025Review
- Physiological Adaptation ofLife (Basel, Switzerland) · 2025Article
- Progress towards a targeted biorefinery ofBiomass conversion and biorefinery · 2024Review
- Circadian rhythm promotes the biomass and amylose hyperaccumulation by mixotrophic cultivation of marine microalga Platymonas helgolandica.Biotechnology for biofuels and bioproducts · 2022Article
- Fine-tuned regulation of photosynthetic performance via γ-aminobutyric acid (GABA) supply coupled with high initial cell density culture for economic starch production in microalgae.Bioresources and bioprocessing · 2022Article
- A brief period of darkness induces changes in fatty acid biosynthesis towards accumulation of saturated fatty acids in Chlorella vulgaris UMT-M1 at stationary growth phase.Biotechnology letters · 2021Article
- Insights into the physiology of Chlorella vulgaris cultivated in sweet sorghum bagasse hydrolysate for sustainable algal biomass and lipid production.Scientific reports · 2021Article
- Influence of spectral intensity and quality of LED lighting on photoacclimation, carbon allocation and high-value pigments in microalgae.Photosynthesis research · 2020Article
- Impact of Cultivation Condition and Media Content onAdvanced pharmaceutical bulletin · 2019Review
- Regulation of Oxygenic Photosynthesis during Trophic Transitions in the Green AlgaThe Plant cell · 2019Article
- Metabolomic Fingerprints of Individual Algal Cells Using the Single-Probe Mass Spectrometry Technique.Frontiers in plant science · 2018Article
- Triacylglycerol is produced from starch and polar lipids in the green alga Dunaliella tertiolecta.Journal of experimental botany · 2017Article
- Rapid Estimation of Astaxanthin and the Carotenoid-to-Chlorophyll Ratio in the Green Microalga Chromochloris zofingiensis Using Flow Cytometry.Marine drugs · 2017Article
- Nitrogen-induced metabolic changes and molecular determinants of carbon allocation in Dunaliella tertiolecta.Scientific reports · 2016Article
- Metabolic regulation of triacylglycerol accumulation in the green algae: identification of potential targets for engineering to improve oil yield.Plant biotechnology journal · 2016Review
- Screening of Diatom Strains and Characterization of Cyclotella cryptica as A Potential Fucoxanthin Producer.Marine drugs · 2016Article
- A new method to manipulate broiler chicken growth and metabolism: Response to mixed LED light system.Scientific reports · 2016Article
- Lipid Production from Nannochloropsis.Marine drugs · 2016Review
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
The objective of this study was to investigate the effect of light on lipid and starch accumulation in the oleaginous green algae Chlorella zofingiensis supplemented with glucose. C. zofingiensis, when fed with 30 g/L glucose, synthesized lipids up to 0.531 g/g dry weight; while in the presence of light, the lipid content dropped down to 0.352 g/g dry weight. Lipid yield on glucose was 0.184 g/g glucose, 14% higher than that cultured with light. The light-mediated lipid reduction was accompanied by the down-regulation of fatty acid biosynthetic genes at the transcriptional level. Furthermore, light promoted cell proliferation, starch accumulation, and the starch yield based on glucose. Taken together, light may attenuate lipid accumulation, possibly through the inhibition of lipid biosynthetic pathway, leading to more carbon flux from glucose to starch. This study reveals the dual effects of light on the sugar-fed C. zofingiensis and provides valuable insights into the possible optimization of algal biomass and lipid production by manipulation of culture conditions.
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