Evidence map›Paper›PMID 26442610›Full record

ArticleLeukemia2015

Bortezomib-thalidomide-dexamethasone (VTD) is superior to bortezomib-cyclophosphamide-dexamethasone (VCD) as induction therapy prior to autologous stem cell transplantation in multiple myeloma.

M Cavo, L Pantani, A Pezzi, M T Petrucci, F Patriarca, F Di Raimondo, G Marzocchi, M Galli, V Montefusco, E Zamagni and 5 more

Registry-linked trialAbstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04612582 (A Comparative Study of Bortezomib-Thalidomide-Dexamethason and Bortezomib-Cyclophosphamide-Dexamethason in the Treatment of Monoclonal Immunoglobulin Light Chain Amyloidosis), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04612582 phase4unknown statusnot on this mapstarted 2020, after this paper: background citation

A Comparative Study of Bortezomib-Thalidomide-Dexamethason and Bortezomib-Cyclophosphamide-Dexamethason in the Treatment of Monoclonal Immunoglobulin Light Chain Amyloidosis: A Prospective Randomized Controlled Trial(BTD-CHINA-TRIAL)

TypeinterventionalSponsorGuangdong Provincial People's HospitalRan2020 to 2023Enrolled70ConditionsImmunoglobulin Light-Chain AmyloidosisArmsThalidomide, Cyclophosphamide
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 71 citations in OpenAlex.

  1. Trial
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  4. Autologous Transplantation, Consolidation, and Maintenance Therapy in Multiple Myeloma: Results of the BMT CTN 0702 Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Trial
  5. Trial
  6. Article
  7. Mobilization Strategies in Myeloma Patients Intended for Autologous Hematopoietic Cell Transplantation.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Therapeutic Advances in Oncology.International journal of molecular sciences · 2021
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Highlights of Abstracts on Plasma Cell Dyscrasia in the Annual Conference ISHBT (Kochi).Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

M CavoSeràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
L PantaniSeràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
A PezziSeràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
M T PetrucciAzienda Policlinico Umberto I, University La Sapienza, Roma, Italy.
F PatriarcaHematology and Bone Marrow Transplant Unit, Udine, Italy.
F Di RaimondoDepartment of Clinical and Molecular Bio-Medicine, University of Catania, Catania, Italy.
G MarzocchiSeràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
M GalliHematology, Papa Giovanni XXIII Hospital, Bergamo, Italy.
V MontefuscoHematology-Bone Marrow Transplantation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
E ZamagniSeràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
B GamberiArcispedale S. Maria Nuova, Hematology, Reggio Emilia, Italy.
P TacchettiSeràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
A BrioliSeràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
A PalumboUniversity of Torino, Azienda Ospedaliero-Universitaria (AOU) S. Giovanni Battista Torino, Torino, Italy.
P SonneveldDepartment of Hematology, Erasmus MC, Rotterdam, The Netherlands.
Azienda Ospedaliero Universitaria San Giovanni Battista · ITErasmus MC · NLFondazione IRCCS Istituto Nazionale dei Tumori · ITOspedale Papa Giovanni XXIII · ITPoliclinico Umberto I · ITUniversity of Catania · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hematopoietic Stem Cell TransplantationAntineoplastic Combined Chemotherapy ProtocolsBortezomibCyclophosphamideDexamethasoneHumansInduction ChemotherapyMultiple MyelomaThalidomideTransplantation, AutologousBortezomibCyclophosphamideDexamethasoneThalidomide

Identifiers

PMID26442610
OpenAlexW2160188479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.