Evidence map›Paper›PMID 26442276›Full record

ArticleFrontiers in surgery2015

Can the Hydroxyapatite-Coated Skin-Penetrating Abutment for Bone Conduction Hearing Implants Integrate with the Surrounding Skin?

Marc van Hoof, Stina Wigren, Hans Duimel, Paul H M Savelkoul, Mark Flynn, Robert Jan Stokroos

Open access · goldAbstract read
In one paragraph

Article in Frontiers in surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Beyond the surface: exploring contributing factors to bone anchored hearing implant complications.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  5. Article
  6. Achieving stomal continence with an ileal pouch and a percutaneous implant.Journal of materials science. Materials in medicine · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The clinical outcome and microbiological profile of bone-anchored hearing systems (BAHS) with different abutment topographies: a prospective pilot study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
  12. Percutaneous bone-anchored hearing implant surgery: dermatome versus linear incision technique.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marc van HoofDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center , Maastricht , Netherlands.
Stina WigrenCochlear Bone Anchored Solutions AB , Mölnlycke , Sweden.
Hans DuimelInstitute of Nanoscopy, Maastricht University Medical Center , Maastricht , Netherlands.
Paul H M SavelkoulDepartment of Medical Microbiology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center , Maastricht , Netherlands ; Department of Medical Microbiology and Infection Control, VU University Medical Center , Amsterdam , Netherlands.
Mark FlynnCochlear Bone Anchored Solutions AB , Mölnlycke , Sweden.
Robert Jan StokroosDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center , Maastricht , Netherlands.
Maastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPercutaneous implants, such as bone conduction hearing implants, suffer from complications that include inflammation of the surrounding skin. A sealed skin-abutment interface can prevent the ingress of bacteria, which should reduce the occurrence of peri-abutment dermatitis. It was hypothesized that a hydroxyapatite (HA)-coated abutment in conjunction with soft tissue preservation surgery should enable integration with the adjacent skin. Previous research has confirmed that integration is never achieved with as-machined titanium abutments. Here, we investigate, in vivo, if skin integration is achievable in patients using a HA-coated abutment. MATERIALS AND

methodsOne titanium abutment (control) and one HA-coated abutment (case) together with the surrounding skin were surgically retrieved from two patients who had a medical indication for this procedure. Histological sections of the skin were investigated using light microscopy. The abutment was qualitatively analyzed using scanning electron microscopy.

resultsThe titanium abutment only had a partial and thin layer of attached amorphous biological material. The HA-coated abutment was almost fully covered by a pronounced thick layer of organized skin, composed of different interconnected structural layers.

conclusionProof-of-principle evidence that the HA-coated abutment can achieve integration with the surrounding skin was presented for the first time.

Indexed as

adverse skin reactionsBahabone conduction hearing implanthistologyhydroxyapatiteSEMskin integration

Identifiers

PMID26442276
PMCPMC4568398
OpenAlexW1939594017

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.