Evidence map›Paper›PMID 26442224›Full record

ArticleCMAJ open

Prevalence and management of osteoarthritis in primary care: an epidemiologic cohort study from the Canadian Primary Care Sentinel Surveillance Network.

Richard Birtwhistle, Rachael Morkem, George Peat, Tyler Williamson, Michael E Green, Shahriar Khan, Kelvin P Jordan

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05543486 (Clinical Evaluation of the Levitation Knee Brace in Patients With Knee Osteoarthritis), which is not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05543486 nacompletednot on this map

Clinical Evaluation of the Levitation Knee Brace in Patients With Knee Osteoarthritis: A Pilot Study

TypeinterventionalSponsorUniversity of CalgaryRan2021 to 2022Enrolled26ConditionsKnee OsteoarthritisArmsLevitation 2 Tri-Compartment Offloader (TCO) knee brace, Knee sleeve
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Richard BirtwhistleCentre for Studies in Primary Care, Department of Family Medicine, Queen's University, Kingston, Ont. ; Department of Public Health Sciences, Queen's University, Kingston, Ont.
Rachael MorkemCentre for Studies in Primary Care, Department of Family Medicine, Queen's University, Kingston, Ont.
George PeatArthiritis Research UK Primary Care Centre, Institute for Primary Care Sciences, Keele University, Staffordshire, UK.
Tyler WilliamsonDepartment of Community Health Sciences, University of Calgary, Calgary, Alta.
Michael E GreenCentre for Studies in Primary Care, Department of Family Medicine, Queen's University, Kingston, Ont. ; Department of Public Health Sciences, Queen's University, Kingston, Ont.
Shahriar KhanCentre for Studies in Primary Care, Department of Family Medicine, Queen's University, Kingston, Ont.
Kelvin P JordanArthiritis Research UK Primary Care Centre, Institute for Primary Care Sciences, Keele University, Staffordshire, UK.
Keele University · GBUniversity of Calgary · CA

Funding

Department of Health RP-PG-0407-10386Medical Research Council G0501798
6 · The paper itself

Abstract

backgroundOsteoarthritis is a common chronic condition that affects many older Canadians and is a considerable cause of disability. Our objective was to describe the epidemiology of osteoarthritis in patients aged 30 years and older using electronic medical records (EMRs) in a Canadian primary care population.

methodsIn this retrospective cohort study, we analyzed the EMRs of 207 610 patients over 30 years of age (extracted on December 31, 2012) who had at least one clinic visit during the preceding 2 years. We calculated the age-sex standardized prevalence of diagnosed osteoarthritis and its association with comorbidities and covariates available in the Canadian Primary Care Sentinel Surveillance Network database.

resultsThe estimated prevalence of diagnosed osteoarthritis was 14.2% (15.6% among women, 12.4% among men). The diagnosis of osteoarthritis was associated with several comorbidities: hypertension (prevalence ratio [PR] 1.17, 95% confidence interval [CI] 1.15-1.18), depression (PR 1.26, 95% CI 1.22-1.3), chronic obstructive pulmonary disease (COPD) (PR 1.16, 95% CI 1.11-1.21) and epilepsy (PR 1.27, 95% CI 1.13-1.43). In addition, 56.6% of patients had received a prescription for a range of nonsteroidal anti-inflammatory drugs, 45% of which were topical. Opioid medications were prescribed to 33% of patients for pain management.

conclusionOsteoarthritis is a common disease in middle-aged and older Canadians. It is more common in women than in men and is associated with comorbid conditions. Most patients with osteoarthritis received pharmacotherapy for inflammation and pain management. As the Canadian population ages, osteoarthritis will become an increasing burden for individuals and the health care system.

Identifiers

PMID26442224
PMCPMC4593417
OpenAlexW2191037725

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.