Evidence map›Paper›PMID 26442123›Full record

ArticleExpert review of endocrinology & metabolism

Optimizing Weight for Maternal and Infant Health - Tenable, or Too Late?

Jacinda M Nicklas, Linda A Barbour

Abstract read
In one paragraph

Article in Expert review of endocrinology & metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. The importance of nutrition in pregnancy and lactation: lifelong consequences.American journal of obstetrics and gynecology · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Nutrition therapy within and beyond gestational diabetes.Diabetes research and clinical practice · 2018
    Review
  13. Obesity in Pregnancy: Optimizing Outcomes for Mom and Baby.The Medical clinics of North America · 2018
    Review
  14. Review
  15. Article
  16. Parturition dysfunction in obesity: time to target the pathobiology.Reproductive biology and endocrinology : RB&E · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jacinda M NicklasDivision of General Internal Medicine, University of Colorado School of Medicine, 12348 E. Montview Blvd, C263, Aurora, CO 80045, 303-724-9028 (work phone), 617-510-7273 (cell phone), 303-724-9976 (fax).
Linda A BarbourProfessor of Medicine and Obstetrics and Gynecology, Divisions of Endocrinology, Metabolism, and Diabetes and Maternal-Fetal Medicine, University of Colorado School of Medicine, Mail Stop 8106, 12801 E. 17 Avenue, Aurora, CO 80045, 303-724-3921 (work phone), 303-594-0474 (cell phone), 303-724-3920 (fax).

Funding

UCHSC: Building Interdisciplinary Research Careers in Women's HealthK12HD057022 · NICHD · UNIVERSITY OF COLORADO DENVER · PI REGENSTEINER, JUDITH G., SANTORO, NANETTE F. · 2007 to 2023
$8.5M
Randomized Trial of Diet in GDM: Metabolic Consequences to Mother and OffspringR01DK101659 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI HERNANDEZ, TERI L · 2014 to 2018
$3.1M
Regulation of Maternal Fuel Supply and Neonatal AdiposityR01DK078645 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BARBOUR, LINDA ANNE · 2010 to 2014
$2.6M
NICHD NIH HHS K12 HD057022NIDDK NIH HHS R01 DK078645NIDDK NIH HHS R01 DK101659
6 · The paper itself

Abstract

Obesity in pregnancy is the leading cause of maternal and fetal morbidity, and gestational weight gain (GWG) is one modifiable risk factor that improves pregnancy outcomes. Most pregnant women gain more than the 2009 Institute of Medicine recommendations, particularly overweight and obese women. GWG even less than the 2009 IOM guidelines in obese women may improve pregnancy outcomes and reduce large-for-gestational-age (LGA) infants, an independent risk factor for childhood obesity, without increasing small-for-gestational-age (SGA) infants. Unfortunately, despite the fact that over 50 interventional trials designed to decrease excess GWG have been conducted, these interventions have been only modestly effective, and interventions designed to facilitate weight postpartum weight loss have also been disappointing. Successful interventions are of paramount importance not only to improve pregnancy outcomes but also for the future metabolic health of the mother and her infant, and may be key in attenuating the trans-generational risk on childhood obesity.

Indexed as

childhood obesitydietfetal programminggestational weight gainInstitute of Medicine guidelinesinterventionslarge for gestational age infantsObesityphysical activitypostpartum weight losspregnancypregnancy outcomes

Identifiers

PMID26442123
PMCPMC4591845

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.