ArticleFrontiers in plant science2015
Modulation of phenolic metabolism under stress conditions in a Lotus japonicus mutant lacking plastidic glutamine synthetase.
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 54 citations in OpenAlex.
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- An Isoflavone Synthase Gene inPlants (Basel, Switzerland) · 2024Article
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- Photorespiration: regulation and new insights on the potential role of persulfidation.Journal of experimental botany · 2023Review
- Role of Promising Secondary Metabolites to Confer Resistance Against Environmental Stresses in Crop Plants: Current Scenario and Future Perspectives.Frontiers in plant science · 2022Review
- Special Issue Editorial: Plant Nitrogen Assimilation and Metabolism.Plants (Basel, Switzerland) · 2021Article
- Flavonoids and Isoflavonoids Biosynthesis in the Model LegumePlants (Basel, Switzerland) · 2020Review
- Response of Phenylpropanoid Pathway and the Role of Polyphenols in Plants under Abiotic Stress.Molecules (Basel, Switzerland) · 2019Review
- A Comparative Metabolomics Analysis Reveals the Tissue-Specific Phenolic Profiling in TwoMolecules (Basel, Switzerland) · 2018Article
- Lipidomics Unravels the Role of Leaf Lipids in Thyme Plant Response to Drought Stress.International journal of molecular sciences · 2017Article
- Deep Sequencing of Suppression Subtractive Hybridisation Drought and Recovery Libraries of the Non-model CropFrontiers in plant science · 2017Article
- Use of transcriptomics and co-expression networks to analyze the interconnections between nitrogen assimilation and photorespiratory metabolism.Journal of experimental botany · 2016Article
- The Combined Effects of Ethylene and MeJA on Metabolic Profiling of Phenolic Compounds in Catharanthus roseus Revealed by Metabolomics Analysis.Frontiers in physiology · 2016Article
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper was aimed to investigate the possible implications of the lack of plastidic glutamine synthetase (GS2) in phenolic metabolism during stress responses in the model legume Lotus japonicus. Important changes in the transcriptome were detected in a GS2 mutant called Ljgln2-2, compared to the wild type, in response to two separate stress conditions, such as drought or the result of the impairment of the photorespiratory cycle. Detailed transcriptomic analysis showed that the biosynthesis of phenolic compounds was affected in the mutant plants in these two different types of stress situations. For this reason, the genes and metabolites related to this metabolic route were further investigated using a combined approach of gene expression analysis and metabolite profiling. A high induction of the expression of several genes for the biosynthesis of different branches of the phenolic biosynthetic pathway was detected by qRT-PCR. The extent of induction was always higher in Ljgln2-2, probably reflecting the higher stress levels present in this genotype. This was paralleled by accumulation of several kaempferol and quercetine glycosides, some of them described for the first time in L. japonicus, and of high levels of the isoflavonoid vestitol. The results obtained indicate that the absence of GS2 affects different aspects of phenolic metabolism in L. japonicus plants in response to stress.
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