ArticleFrontiers in microbiology2015
Insights into arsenic multi-operons expression and resistance mechanisms in Rhodopseudomonas palustris CGA009.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 52 citations in OpenAlex.
- Assessing Fluoroacetate Defluorination Potential across Diverse Enzymes Using Quantum Chemistry.The journal of physical chemistry. B · 2026Article
- Electricity-Induced SimultaneousACS ES&T water · 2026Article
- Quantifying arsenic-binding affinities of ArsR proteins via biomimetic self-assembly.Frontiers in microbiology · 2026Article
- Proteomic Analysis of Arsenic Resistance during Cyanide Assimilation byInternational journal of molecular sciences · 2023Article
- Biotechnology Advances in Bioremediation of Arsenic: A Review.Molecules (Basel, Switzerland) · 2023Review
- Structural and functional mapping ofComputational and structural biotechnology journal · 2023Article
- Meta-omics-aided isolation of an elusive anaerobic arsenic-methylating soil bacterium.The ISME journal · 2022Article
- Bacterial Arsenic Metabolism and Its Role in Arsenic Bioremediation.Current microbiology · 2022Review
- Characteristics and Application ofFrontiers in bioengineering and biotechnology · 2022Review
- Genomic Variation and Arsenic Tolerance Emerged as Niche Specific Adaptations by DifferentFrontiers in microbiology · 2020Article
- Diversity and abundance of arsenic methylating microorganisms in high arsenic groundwater from Hetao Plain of Inner Mongolia, China.Ecotoxicology (London, England) · 2018Article
- Analysis of the ars gene cluster from highly arsenic-resistant Burkholderia xenovorans LB400.World journal of microbiology & biotechnology · 2018Article
- Genetic diversity and characterization of arsenic-resistant endophytic bacteria isolated from Pteris vittata, an arsenic hyperaccumulator.BMC microbiology · 2018Article
- Distribution of Arsenic Resistance Genes in Prokaryotes.Frontiers in microbiology · 2018Review
- Arsenic Methylation and its Relationship to Abundance and Diversity of arsM Genes in Composting Manure.Scientific reports · 2017Article
- Arsenic Detoxification by Geobacter Species.Applied and environmental microbiology · 2017Article
- Comparative Genomic Analysis Reveals Organization, Function and Evolution ofFrontiers in microbiology · 2017Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arsenic (As) is widespread in the environment and causes numerous health problems. Rhodopseudomonas palustris has been regarded as a good model organism for studying arsenic detoxification since it was first demonstrated to methylate environmental arsenic by conversion to soluble or gaseous methylated species. However, the detailed arsenic resistance mechanisms remain unknown though there are at least three arsenic-resistance operons (ars1, ars2, and ars3) in R. palustris. In this study, we investigated how arsenic multi-operons contributed to arsenic detoxification in R. palustris. The expression of ars2 or ars3 operons increased with increasing environmental arsenite (As(III)) concentrations (up to 1.0 mM) while transcript of ars1 operon was not detected in the middle log-phase (55 h). ars2 operon was actively expressed even at the low concentration of As(III) (0.01 μM), whereas the ars3 operon was expressed at 1.0 μM of As(III), indicating that there was a differential regulation mechanism for the three arsenic operons. Furthermore, ars2 and ars3 operons were maximally transcribed in the early log-phase where ars2 operon was 5.4-fold higher than that of ars3 operon. A low level of ars1 transcript was only detected at 43 h (early log-phase). Arsenic speciation analysis demonstrated that R. palustris could reduce As(V) to As(III). Collectively, strain CGA009 detoxified arsenic by using arsenic reduction and methylating arsenic mechanism, while the latter might occur with the presence of higher concentrations of arsenic.
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