ArticleFrontiers in physiology2015
Stem cell origin differently affects bone tissue engineering strategies.
Article in Frontiers in physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
23 citing papers in PubMed, 44 citations in OpenAlex.
- Induction of Cellular Senescence by Pesticide Exposure in Human Umbilical Vein Endothelial Cells (HUVECs): Impacts on Telomerase Length, Cellular Morphology, and mtDNA Variation.Journal of cellular physiology · 2026Article
- Reinforcing Restorative Dentistry: The Dual Role of Carbon Nanotubes in Material Enhancement and Therapy.International journal of dentistry · 2025Review
- MicroRNA functions in osteogenic differentiation of periodontal ligament stem cells: a scoping review.Frontiers in oral health · 2025Review
- Editorial: Stem cells in oral cavity: from development to regeneration, Volume II.Frontiers in cell and developmental biology · 2023Article
- Smoking Cessation on Periodontal and Peri-Implant Health Status: A Systematic Review.Dentistry journal · 2022Review
- Editorial: Stem Cells in Oral Cavity: From Development to Regeneration.Frontiers in cell and developmental biology · 2022Article
- Assessment of the structural and functional characteristics of human mesenchymal stem cells associated with a prolonged exposure of morphine.Scientific reports · 2021Article
- Osteogenic differentiation of human mesenchymal stromal cells and fibroblasts differs depending on tissue origin and replicative senescence.Scientific reports · 2021Article
- A Critical Review on the Design, Manufacturing and Assessment of the Bone Scaffold for Large Bone Defects.Frontiers in bioengineering and biotechnology · 2021Review
- The Bone-Forming Properties of Periosteum-Derived Cells Differ Between Harvest Sites.Frontiers in cell and developmental biology · 2020Article
- Article
- Titanium Surface Properties Influence the Biological Activity and FasL Expression of Craniofacial Stromal Cells.Stem cells international · 2019Article
- Wharton's Jelly Derived Mesenchymal Stem Cells: Comparing Human and Horse.Stem cell reviews and reports · 2018Article
- The Hypoxia-Mimetic Agent Cobalt Chloride Differently Affects Human Mesenchymal Stem Cells in Their Chondrogenic Potential.Stem cells international · 2018Article
- In Vitro and In Vivo Studies of Alar-Nasal Cartilage Using Autologous Micro-Grafts: The Use of the RigeneraPharmaceuticals (Basel, Switzerland) · 2017Article
- Methods of Isolation and Characterization of Stem Cells from Different Regions of Oral Cavity Using Markers: A Systematic Review.International journal of stem cells · 2017Review
- Challenges of bone tissue engineering in orthopaedic patients.World journal of orthopedics · 2017Article
- Emerging Perspectives in Scaffold for Tissue Engineering in Oral Surgery.Stem cells international · 2017Review
- Strategies Developed to Induce, Direct, and Potentiate Bone Healing.Frontiers in physiology · 2017Review
- Autologous Periosteum-Derived Micrografts and PLGA/HA Enhance the Bone Formation in Sinus Lift Augmentation.Frontiers in cell and developmental biology · 2017Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone tissue engineering approaches are encouraging for the improvement of conventional bone grafting technique drawbacks. Thanks to their self-renewal and multi-lineage differentiation ability, stem cells are one of the major actors in tissue engineering approaches, and among these adult mesenchymal stem cells (MSCs) hold a great promise for regenerative medicine strategies. Bone marrow MSCs (BM-MSCs) are the first- identified and well-recognized stem cell population used in bone tissue engineering. Nevertheless, several factors hamper BM-MSC clinical application and subsequently, new stem cell sources have been investigated for these purposes. The fruitful selection and combination of tissue engineered scaffold, progenitor cells, and physiologic signaling molecules allowed the surgeon to reconstruct the missing natural tissue. On the basis of these considerations, we analyzed the capability of two different scaffolds, planned for osteochondral tissue regeneration, to modulate differentiation of adult stem cells of dissimilar local sources (i.e., periodontal ligament, maxillary periosteum) as well as adipose-derived stem cells (ASCs), in view of possible craniofacial tissue engineering strategies. We demonstrated that cells are differently committed toward the osteoblastic phenotype and therefore, taking into account their specific features, they could be intriguing cell sources in different stem cell-based bone/periodontal tissue regeneration approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.