Evidence map›Paper›PMID 26441646›Full record

ReviewFrontiers in pharmacology2015

Advances in optical imaging for pharmacological studies.

Alicia Arranz, Jorge Ripoll

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Insight of smart biosensors for COVID-19: A review.Luminescence : the journal of biological and chemical luminescence · 2023
    Review
  7. Article
  8. Spatiotemporal tracking of gold nanorods after intranasal administration for brain targeting.Journal of controlled release : official journal of the Controlled Release Society · 2023
    Article
  9. Article
  10. Medical Imaging Technology and Imaging Agents.Advances in experimental medicine and biology · 2023
    Article
  11. Review
  12. ClickablePharmaceuticals (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Nanotechnology-Assisted Cell Tracking.Nanomaterials (Basel, Switzerland) · 2022
    Review
  15. Perfluorooctyl bromide nanoemulsions holding MnOActa pharmaceutica Sinica. B · 2022
    Article
  16. Aptamers-Diagnostic and Therapeutic Solution in SARS-CoV-2.International journal of molecular sciences · 2022
    Review
  17. Review
  18. Optical Biosensors for Virus Detection: Prospects for SARS-CoV-2/COVID-19.Chembiochem : a European journal of chemical biology · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alicia ArranzDepartment of Cell Biology and Immunology, Center for Molecular Biology "Severo Ochoa", Spanish National Research Council , Madrid, Spain.
Jorge RipollDepartment of Bioengineering and Aerospace Engineering, Universidad Carlos III of Madrid , Madrid, Spain ; Experimental Medicine and Surgery Unit, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón , Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging approaches are an essential tool for following up over time representative parameters of in vivo models, providing useful information in pharmacological studies. Main advantages of optical imaging approaches compared to other imaging methods are their safety, straight-forward use and cost-effectiveness. A main drawback, however, is having to deal with the presence of high scattering and high absorption in living tissues. Depending on how these issues are addressed, three different modalities can be differentiated: planar imaging (including fluorescence and bioluminescence in vivo imaging), optical tomography, and optoacoustic approaches. In this review we describe the latest advances in optical in vivo imaging with pharmacological applications, with special focus on the development of new optical imaging probes in order to overcome the strong absorption introduced by different tissue components, especially hemoglobin, and the development of multimodal imaging systems in order to overcome the resolution limitations imposed by scattering.

Indexed as

bioluminescencedata processingfluorescence molecular tomographyhybrid systemsmultispectral imagingmultispectral optoacoustic tomographyoptoacousticsplanar fluorescence imaging

Identifiers

PMID26441646
PMCPMC4566037

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.