ReviewFrontiers in neural circuits2015
The olfactory thalamus: unanswered questions about the role of the mediodorsal thalamic nucleus in olfaction.
Review in Frontiers in neural circuits, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The scent of emotions: A systematic review of human intra- and interspecific chemical communication of emotions.Brain and behavior · 2020Pooled it
- Control of associative learning by the mediodorsal thalamus-orbitofrontal cortex circuit.Nature communications · 2026Article
- Brain Spatial Genomics Atlases.Genes · 2026Review
- Structural and diffusion imaging in olfactory-related brain regions in Parkinson's disease: predictors of clinical progression.Scientific reports · 2025Article
- The neural circuit mechanism for auditory responses in the mediodorsal thalamic nucleus of awake mice.Communications biology · 2025Article
- The Bulb, the Brain and the Being: New Insights into Olfactory System Anatomy, Organization and Connectivity.Brain sciences · 2025Article
- Distinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction.Molecular brain · 2025Article
- Article
- Cerebral microstructural alterations in Post-COVID-condition are related to cognitive impairment, olfactory dysfunction and fatigue.Nature communications · 2024Article
- Olfactory neurofeedback: current state and possibilities for further development.Frontiers in human neuroscience · 2024Article
- Functional connectivity patterns in parosmia.Behavioral and brain functions : BBF · 2023Article
- Thalamic gray matter volume mediates the association between KIBRA polymorphism and olfactory function among older adults: a population-based study.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Translational Considerations in the Development of Intranasal Treatments for Epilepsy.Pharmaceutics · 2023Review
- Overnight olfactory enrichment using an odorant diffuser improves memory and modifies the uncinate fasciculus in older adults.Frontiers in neuroscience · 2023Review
- Retinorecipient areas in the common marmoset (Frontiers in neural circuits · 2023Review
- Magnetic resonance imaging findings in COVID-19-related anosmia.Turkish journal of medical sciences · 2022Article
- Olfactory modulation of the medial prefrontal cortex circuitry: Implications for social cognition.Seminars in cell & developmental biology · 2022Review
- Intranasal drug delivery: opportunities and toxicologic challenges during drug development.Drug delivery and translational research · 2022Review
- Reciprocal relationships between sleep and smell.Frontiers in neural circuits · 2022Review
- Thalamic activations in rat brain by fMRI during tactile (forepaw, whisker) and non-tactile (visual, olfactory) sensory stimulations.PloS one · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The mediodorsal thalamic nucleus (MDT) is a higher order thalamic nucleus and its role in cognition is increasingly well established. Interestingly, components of the MDT also have a somewhat unique sensory function as they link primary olfactory cortex to orbitofrontal associative cortex. In fact, anatomical evidence firmly demonstrates that the MDT receives direct input from primary olfactory areas including the piriform cortex and has dense reciprocal connections with the orbitofrontal cortex. The functions of this olfactory pathway have been poorly explored but lesion, imaging, and electrophysiological studies suggest that these connections may be involved in olfactory processing including odor perception, discrimination, learning, and attention. However, many important questions regarding the MDT and olfaction remain unanswered. Our goal here is not only to briefly review the existing literature but also to highlight some of the remaining questions that need to be answered to better define the role(s) of the MDT in olfactory processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.