ArticleStatistical modelling2015
Cox Regression Models with Functional Covariates for Survival Data.
Article in Statistical modelling, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Impact of Radiation on Locoregional Control in Women with Node-Positive Breast Cancer Treated with Neoadjuvant Chemotherapy and Axillary Lymph Node Dissection: Results from ACOSOG Z1071 Clinical Trial.International journal of radiation oncology, biology, physics · 2019Trial
- Shape-Based Partially Linear Single-Index Cox Model for Alzheimer's Disease Conversion.Statistics in medicine · 2026Article
- Joint analysis of longitudinal and recurrent event data: A functional regression approach with autoregressive frailty.Statistical methods in medical research · 2026Article
- Elastic functional Cox regression model with shape predictors.Journal of applied statistics · 2026Article
- Semiparametric Joint Modeling for Survival Analysis with Longitudinal Covariates.Journal of the American Statistical Association · 2026Article
- Tutorial on Bayesian Functional Regression Using Stan.Statistics in medicine · 2025Article
- Quantile index predictors using R package hyper.gam.Bioinformatics (Oxford, England) · 2025Article
- Bayesian Estimation of Partial Functional Tobit Censored Quantile Regression Model.Statistics in medicine · 2025Article
- Functional protein biomarkers based on distributions of expression levels in single-cell imaging data.Bioinformatics (Oxford, England) · 2025Article
- Quantile Index Biomarkers Based on Single-Cell Expression Data.Laboratory investigation; a journal of technical methods and pathology · 2023Article
- Forecasting ICU Census by Combining Time Series and Survival Models.Critical care explorations · 2023Article
- Predicting the onset of breast cancer using mammogram imaging data with irregular boundary.Biostatistics (Oxford, England) · 2023Article
- Additive Functional Cox Model.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2021Article
- Organizing and analyzing the activity data in NHANES.Statistics in biosciences · 2019Article
- Dynamic predictions in Bayesian functional joint models for longitudinal and time-to-event data: An application to Alzheimer's disease.Statistical methods in medical research · 2019Article
- CancerClock: A DNA Methylation Age Predictor to Identify and Characterize Aging Clock in Pan-Cancer.Frontiers in bioengineering and biotechnology · 2019Article
- FLCRM: Functional linear cox regression model.Biometrics · 2018Article
- Functional joint model for longitudinal and time-to-event data: an application to Alzheimer's disease.Statistics in medicine · 2017Article
- A comparison of risk prediction methods using repeated observations: an application to electronic health records for hemodialysis.Statistics in medicine · 2017Article
- Distribution and prognostic significance of myelotoxicity in newly diagnosed glioblastoma in a real-life cohort: Time to treat more aggressively?Neuro-oncology advancesArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We extend the Cox proportional hazards model to cases when the exposure is a densely sampled functional process, measured at baseline. The fundamental idea is to combine penalized signal regression with methods developed for mixed effects proportional hazards models. The model is fit by maximizing the penalized partial likelihood, with smoothing parameters estimated by a likelihood-based criterion such as AIC or EPIC. The model may be extended to allow for multiple functional predictors, time varying coefficients, and missing or unequally-spaced data. Methods were inspired by and applied to a study of the association between time to death after hospital discharge and daily measures of disease severity collected in the intensive care unit, among survivors of acute respiratory distress syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.