ReviewPituitary2016
Nationwide shift from microscopic to endoscopic transsphenoidal pituitary surgery.
Review in Pituitary, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Unlocking surgical precision: intraoperative MRI in endoscopic skull base surgery, a meta-analysis.Neurosurgical review · 2026Pooled it
- Postsurgical outcomes of nonfunctioning pituitary adenomas: a patient-level meta-analysis.Pituitary · 2023Pooled it
- Effects of Infraorbital Nerve Block with Dexmedetomidine-Added Bupivacaine on Intraoperative Opioid Consumption and Postoperative Analgesia During Endoscopic Transsphenoidal Surgery: A Prospective, Randomized, Double-Blind Controlled Trial.Journal of pain research · 2026Trial
- Preoperative carbohydrate fluid intake reduces postoperative nausea and vomiting without increasing gastric volume in neuroendoscopic sellar tumor surgery.European journal of medical research · 2025Trial
- Surgical Experience and Validation of the "Bow Tie" Trilayer Graft Technique for Closure of Anterior Skull Base Defects.Laryngoscope investigative otolaryngology · 2025Article
- Article
- Cost outcomes of pituitary adenoma resection: The use of a hybrid microscopic/endoscopic surgery.Surgical neurology international · 2025Article
- Assessing surgical outcomes in pituitary adenoma: A comparison of microscopic and endoscopic techniques.Surgical neurology international · 2025Article
- Risk Factors for Isolated Sphenoid Sinusitis after Endoscopic Endonasal Transsphenoidal Pituitary Surgery.Diagnostics (Basel, Switzerland) · 2024Article
- Sinonasal Outcomes of the Combined Transseptal/Transnasal Approach with Unilateral Nasoseptal Rescue Flap in Endoscopic Endonasal Transsphenoidal Surgery: A Propensity Score Matching Analysis.Journal of neurological surgery. Part B, Skull base · 2024Article
- Deep learning based identification of pituitary adenoma on surgical endoscopic images: a pilot study.Neurosurgical review · 2023Article
- Characteristics of inflammatory and infectious diseases of the pituitary gland in patients undergoing transsphenoidal surgery.Pituitary · 2023Article
- Evolution of Radiographic Changes of a Vascularized Pedicled Nasoseptal Flap after Endonasal Endoscopic Skull Base Surgery.AJNR. American journal of neuroradiology · 2023Article
- [Application of ethmoid artery pedicled septal floor mucosa flap in repair of postoperative cerebrospinal fluid leak after transsphenoidal pituitary surgery].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023Article
- Recommendation to improve the WHO classification of posterior pituitary tumors as a unique entity: evidence from a large case series.Endocrine connections · 2022Article
- What is the current clinical practice in pituitary adenoma surgery in Europe? European Pituitary Adenoma Surgery Survey (EU-PASS) results-technical part.Neurosurgical review · 2022Article
- Utilizing a Novel Pituitary Retractor for Early Descent of the Diaphragma Sellae during Endoscopic Transsphenoidal Pituitary Surgery.Journal of Korean Neurosurgical Society · 2022Article
- Analysis of neuroendoscopy for the treatment of macroadenomas and giant pituitary adenomas.Frontiers in surgery · 2022Article
- Application of dural suturing in the endoscopic endonasal approach to the sellar region.Frontiers in surgery · 2022Article
- Characteristics and overall survival in pediatric versus adult pituitary adenoma: a National Cancer Database analysis.Pituitary · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purposeTranssphenoidal pituitary surgery can be carried out with either an operating microscope or with an endoscope, but the relative frequency of both techniques is unknown.
methodsAll microscopic and endoscopic transsphenoidal pituitary surgeries were extracted from the Centers for Medicare and Medicaid Services Part B data files between the years 2003 and 2013. National and state-level trends were compared over time.
resultsEndoscopic surgery significantly increased and microscopic surgery significantly decreased over the years 2003-2013. Thirty-eight of 48 states increased their use of endoscopic surgery, while 38 of 48 states decreased their use of microscopic surgery.
conclusionsNationwide data show a clear trend for an increasing use of endoscopic transsphenoidal surgery at the expense of microscopic surgery. The underlying causes of these trends are unknown, but clearly deserve further investigation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.