Evidence map›Paper›PMID 26440935›Full record

Observational studyRheumatology international2016

The prevalence of monosodium urate and calcium pyrophosphate crystals in synovial fluid from wrist and finger joints.

Paola Galozzi, Francesca Oliviero, Paola Frallonardo, Marta Favero, Ariela Hoxha, Anna Scanu, Mariagrazia Lorenzin, Augusta Ortolan, Leonardo Punzi, Roberta Ramonda

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Rheumatology international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Paola GalozziRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Francesca OlivieroRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Paola FrallonardoRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Marta FaveroRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Ariela HoxhaRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Anna ScanuRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Mariagrazia LorenzinRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Augusta OrtolanRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Leonardo PunziRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Roberta RamondaRheumatology Unit, Department of Medicine - DIMED, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy. roberta.ramonda@unipd.it.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the frequency of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluids (SFs) aspirated from wrist and finger joints of patients with previously diagnosed joint diseases. We reviewed the results of SF analysis of 1593 samples and identified 126 patients with effusions in the small joints of the hands and wrists. We reported from patients' medical files data about sex, age, diagnosis, disease duration and the microscopic SF results. The prevalence of CPP crystals in SF was 85.71% in CPP-crystals arthritis (CPP-CA), 19.35% in rheumatoid arthritis (RA), 13.89% in osteoarthritis (OA) and 0% in psoriatic arthritis (PsA), spondyloarthritis (SpA), gout and miscellanea. The prevalence of MSU crystals in SF was 83.3% in gout, 10% in PsA, 2.8% in OA and 0% in RA, SpA, miscellanea and CPP-CA. Consistent with previously reported data concerning the big joints, microcrystals can be frequently found also in the small joints of patients with previous diagnosis. The finding underlines the importance of analyzing SF from the hand and wrist joints in the attempt to identify comorbidities associated with the presence of crystals and to develop targeted treatment strategies.

Indexed as

AdultAgedAged, 80 and overCalcium PyrophosphateComorbidityCrystallizationFemaleFinger JointHumansJoint DiseasesMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRheumatic DiseasesSynovial FluidCalcium PyrophosphateUric AcidHand diseasesMonosodium urate crystalsPyrophosphate crystalsSynovial fluid

Identifiers

PMID26440935
OpenAlexW1705003327

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.