Evidence map›Paper›PMID 26440731›Full record

ArticleThe pharmacogenomics journal2016

Clinical pharmacology of tenofovir clearance: a pharmacokinetic/pharmacogenetic study on plasma and urines.

A Calcagno, J Cusato, L Marinaro, L Trentini, C Alcantarini, M Mussa, M Simiele, A D'Avolio, G Di Perri, S Bonora

Abstract read
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In one paragraph

Article in The pharmacogenomics journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

A CalcagnoUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
J CusatoUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
L MarinaroUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
L TrentiniUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
C AlcantariniUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
M MussaUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
M SimieleUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
A D'AvolioUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
G Di PerriUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
S BonoraUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Turin, Italy.
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The HIV virus and hepatitis B virus nucleotide reverse transcriptase inhibitor tenofovir has been associated with proximal tubular toxicity; the latter was found to be predicted by plasma concentrations and with single-nucleotide polymorphisms in transporters-encoding genes. A cross-sectional analysis in adult HIV-positive patients with estimated creatinine clearance >60 ml min

Indexed as

Pharmacogenomic VariantsPolymorphism, Single NucleotideAdultAnti-HIV AgentsATP-Binding Cassette, Sub-Family C ProteinsCreatinineCross-Sectional StudiesDrug InteractionsDrug Therapy, CombinationFemaleHeterozygoteHomozygoteHumansKidneyLinear ModelsMaleABCC10 protein, humanAnti-HIV AgentsATP-Binding Cassette, Sub-Family C Proteinscif nucleoside transporterCreatinineMembrane Transport ProteinsProtease InhibitorsReverse Transcriptase InhibitorsTenofovir

Identifiers

PMID26440731
OpenAlexW2418633964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.