ReviewClinical microbiology reviews1989
Clinical and laboratory aspects of filariasis.
Review in Clinical microbiology reviews, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 72 citations in OpenAlex.
- Lymphatic filariasis remained silent until presentation with huge abdominal mass mimicking malignancy: a case report.ASM case reports · 2025Article
- Three isoforms ofmicroPublication biology · 2025Article
- Beyond Tradition: Exploring Cutting-Edge Approaches for Accurate Diagnosis of Human Filariasis.Pathogens (Basel, Switzerland) · 2024Review
- Breast filariasis presenting fibroadenoma like nodules: a rare diagnosis.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Evaluation of LAMP for the diagnosis of Loa loa infection in dried blood spots compared to PCR-based assays and microscopy.Memorias do Instituto Oswaldo Cruz · 2022Article
- Recombinant antigens used as diagnostic tools for lymphatic filariasis.Parasites & vectors · 2021Review
- Diagnostic Identification and Differentiation of Microfilariae.Journal of clinical microbiology · 2019Review
- Filariasis serosurvey, New Caledonia, South Pacific, 2013.Parasites & vectors · 2015Article
- Relevance of the eosinophil blood count in bancroftian filariasis as a screening tool for the treatment.Pathogens and global health · 2013Article
- Article
- Distribution of Brugia malayi larvae and DNA in vector and non-vector mosquitoes: implications for molecular diagnostics.Parasites & vectors · 2009Article
- An oral recombinant vaccine in dogs against Echinococcus granulosus, the causative agent of human hydatid disease: a pilot study.PLoS neglected tropical diseases · 2008Article
- The treatment of chyluria secondary to advanced carcinoma of the prostate.Prostate cancer and prostatic diseases · 2008Article
- Transmission of tropical and geographically restricted infections during solid-organ transplantation.Clinical microbiology reviews · 2008Review
- B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites.The Journal of experimental medicine · 2000Article
- Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice.The American journal of pathology · 1995Article
- Tropical medicine.Postgraduate medical journal · 1991Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human filarial infections afflict over 150 million persons worldwide and are major causes of morbidity in many developing countries. Onchocerca volvulus infection is a leading preventable cause of blindness, while bancroftian and brugian filariasis may produce lymphatic obstruction of the genitalia and extremities (elephantiasis). Definitive diagnosis of these helminthic infections currently depends on demonstration of microfilariae in host tissues, i.e., the skin in the case of O. volvulus and the bloodstream in the cases of Wuchereria bancrofti and Brugia malayi. Many investigations are now directed at developing specific and sensitive serum antigen assays that will allow diagnosis of active infection (i.e., presence of adult-stage parasites) in the absence of detectable microfilariae. With respect to the immunology of these parasitic infections, efforts are being directed at elucidating the role of T- and B-cell responses in the development of pathologic lesions and resistance to reinfection. These data as well as molecular biologic approaches to identify and study filarial molecules which are immunogenic are discussed. Finally, since treatment of filariases at present depends on antiparasitic drugs, the clinical indications and dosages of diethylcarbamazine and ivermectin are summarized.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.