ArticleJournal of neuroimmunology2015
Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis.
Article in Journal of neuroimmunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Exploring autoantigens in autoimmune limbic encephalitis using phage immunoprecipitation sequencing.Journal of neurology · 2025Article
- Deciphering the host genetic factors conferring susceptibility to severe COVID-19 using exome sequencing.Genes and immunity · 2024Article
- The role of the adenylate kinase 5 gene in various diseases and cancer.Journal of clinical and translational science · 2024Review
- Anti-adenylate kinase 5 encephalitis: Clinical characteristics, diagnosis, and management of this rare entity.Journal of translational autoimmunity · 2023Review
- The role of the CD8+ T cell compartment in ageing and neurodegenerative disorders.Frontiers in immunology · 2023Review
- Adenylate kinase 5 (AK5) autoimmune encephalitis: Clinical presentations and outcomes in three new patients.Journal of neuroimmunology · 2022Article
- Distinctive clinical presentation and pathogenic specificities of anti-AK5 encephalitis.Brain : a journal of neurology · 2021Article
- Anti-Adenylate Kinase 5 Encephalitis With Histologic Evidence of CNS Vasculitis.Neurology(R) neuroimmunology & neuroinflammation · 2021Article
- Autoimmune encephalitis with psychiatric features in adults: historical evolution and prospective challenge.Journal of neural transmission (Vienna, Austria : 1996) · 2021Review
- Conventional brain MRI features distinguishing limbic encephalitis from mesial temporal glioma.Neuroradiology · 2019Article
- Adenylate Kinase: A Ubiquitous Enzyme Correlated with Medical Conditions.The protein journal · 2019Review
- Isolated seizures are a common early feature of paraneoplastic anti-GABAJournal of neurology · 2019Observational
- A Genome-Wide Search for Bipolar Disorder Risk Loci Modified by Mitochondrial Genome Variation.Molecular neuropsychiatry · 2018Article
- Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis.Acta neuropathologica communications · 2017Article
- Article
- Rapidly Progressive Dementia.Continuum (Minneapolis, Minn.) · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Autoantibodies associated with autoimmune limbic encephalitis (ALE) have been well-characterized, with intracellular neuronal antibodies being less responsive to immunotherapy than antibodies to cell surface antigens. Adenylate kinase 5 (AK5) is a nucleoside monophosphate kinase vital for neuronal-specific metabolism and is located intracellularly in the cytosol and expressed exclusively in the brain. Antibodies to AK5 had been previously identified but were not known to be associated with human disease prior to the report of two patients with AK5-related ALE (Tuzun et al., 2007). We present the complete clinical picture for one of these patients and the first reported neuropathology for AK5 ALE.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.