ArticlePloS one2015
Nickel Allergy Is a Risk Factor for Endometriosis: An 11-Year Population-Based Nested Case-Control Study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Systemic Nickel Allergy Syndrome.American journal of medicine open · 2026Review
- Diet in Prevention and Treatment of Endometriosis: Current State of Knowledge.Current nutrition reports · 2024Review
- How Can Selected Dietary Ingredients Influence the Development and Progression of Endometriosis?Nutrients · 2024Review
- Holistic approaches to living well with endometriosis.F1000Research · 2024Review
- Correlation between Endometriosis and Selected Allergic and Autoimmune Diseases and Eating Habits.Medicina (Kaunas, Lithuania) · 2022Article
- Dienogest and the Risk of Reoperation in Endometriosis.Journal of personalized medicine · 2021Article
- Update of the risk assessment of nickel in food and drinking water.EFSA journal. European Food Safety Authority · 2020Article
- Article
- Knockdown of vascular cell adhesion molecule 1 impedes transforming growth factor beta 1-mediated proliferation, migration, and invasion of endometriotic cyst stromal cells.Reproductive biology and endocrinology : RB&E · 2019Article
- Suppressive regulatory T cells and latent transforming growth factor-β-expressing macrophages are altered in the peritoneal fluid of patients with endometriosis.Reproductive biology and endocrinology : RB&E · 2018Article
- Nickel-resistant bacteria isolated in human microbiome.New microbes and new infections · 2017Article
- Nickel allergy in lipid transfer protein sensitized patients: Prevalence and clinical features.International journal of immunopathology and pharmacologyObservational
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA cross-sectional study has reported that nickel allergy is associated with endometriosis. However, causal studies of this association are limited.
objectiveThe objective of this study was to compare the prevalence of nickel allergy in women with and without endometriosis.
methodsWe used a National Health Insurance Service (NHIS) sample cohort dataset that included approximately 1 million individuals from South Korea; the data were obtained between January 01, 2002, and December 31, 2013. We selected the endometriosis group according to diagnosis code (N80.X), surgery codes, and drug codes during the years 2009~2013. The controls were randomly matched to the endometriosis patients at a ratio of 4:1 by age and socioeconomic status. Patients with nickel allergy were defined in the cohort dataset as those with a simultaneous diagnosis code (L23.0) and patch test code during 2002~2008.
resultsIn total, 4,985 women were selected from the NHIS cohort database and divided into an endometriosis group (997 women) and a control group (3,988 women). The number of patients with nickel allergy in the endometriosis group was eight (0.8%), and that in the control group was thirteen (0.3%). After adjustment for age and socioeconomic status, the rate of nickel allergy in was higher in the endometriosis group than in the control group [odds ratio: 2.474; 95% confidence interval: 1.023~5.988; p = 0.044].
conclusionsWe found that nickel allergy is a risk factor for endometriosis.
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