ReviewCerebellum (London, England)2016
Consensus Paper: Cerebellar Development.
Open access · hybridAbstract readReviewConsensus Statement
In one paragraph
Review in Cerebellum (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 270 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
270citing papers in PubMed, 1 pooled it
43.7field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
270 citing papers in PubMed, 1 synthesis or guideline pooled it, 487 citations in OpenAlex.
- A bias-accounting meta-analytic approach refines and expands the cerebellar behavioral topography.Neuroscience and biobehavioral reviews · 2025Pooled it
- Comprehensive mapping of Neurofibromin (NF1) expression in developing mouse brain.Brain structure & function · 2026Article
- Novel neonatal hypoxic-ischemic model demonstrates glial activation and memory deficits without neuronal loss.Pediatric research · 2026Article
- Computational investigation of mechanical mechanisms underlying diverse cerebellar lobular morphologies.Biomechanics and modeling in mechanobiology · 2026Article
- Differentially Methylated Regions in Human Rhombic Lip Compartments Are Enriched in Putative Active Enhancers, Human Accelerated Regions, and Medulloblastoma Copy Number Aberrations.Cerebellum (London, England) · 2026Article
- Posterior Fossa Malformations in a Cohort of 116 Fetuses: A Retrospective Analysis of Imaging Characteristics, Postnatal Imaging Concordance, Pregnancy Outcomes and Yield of Genetic Testing.Cerebellum (London, England) · 2026Article
- GNOMES: an integrated framework for genome-wide normalization and differential binding analysis of CUT&RUN and ChIP-seq data.bioRxiv : the preprint server for biology · 2026Article
- Integration of human and mouse single-cell transcriptomes of the developing cerebellum nominates cells-of-origin for group 3 and 4 medulloblastoma.BMC cancer · 2026Article
- Comprehensive mapping of Neurofibromin (NF1) expression in developing mouse brain.bioRxiv : the preprint server for biology · 2026Article
- Ethanol disrupts cerebellar synaptic modulation by enhancing EAAT4-mediated glutamate uptake.Communications biology · 2026Article
- ACSS2 mediates prenatal alcohol exposure-related morphological and behavioral phenotypes.Neurobiology of disease · 2026Article
- Purkinje cell intrinsic activity shapes cerebellar development and function.Nature communications · 2026Article
- Cerebellar tonic inhibition orchestrates the maturation of information processing and motor coordination.Experimental & molecular medicine · 2026Article
- Epigenetic control of microglial developmental milestones from proliferative progenitors to efficient phagocytes.Research square · 2026Article
- Article
- Arhgef7 is essential for granule cell precursor proliferation and migration during cerebellum development.iScience · 2026Article
- Spatiotemporal histogenesis of the developing human cerebellum reveals dynamic layering of Bergmann glia.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Generating cerebellar organoids from pluripotent stem cells.Disease models & mechanisms · 2026Review
- Modeling diffuse midline glioma through triple-electrode in utero electroporation of the developing mouse pons.PloS one · 2026Article
- Genetic Insights in Hindbrain Abnormalities Through Network Analysis Expose Key Biological Pathways in Hindbrain Development.Cerebellum (London, England) · 2025Article
210 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 20 institutions in 8 countries.
Ketty LetoDepartment of Neuroscience Rita Levi Montalcini, University of Turin, via Cherasco 15, 10026, Turin, Italy. ketty.leto@unito.it.
Marife ArancilloDepartments of Pathology & Immunology and Neuroscience, Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute of Texas Children's Hospital, 1250 Moursund Street, Suite 1325, Houston, TX, 77030, USA.
Esther B E BeckerMedical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, UK.
Annalisa BuffoDepartment of Neuroscience Rita Levi Montalcini, University of Turin, via Cherasco 15, 10026, Turin, Italy.
Chin ChiangDepartment of Cell and Developmental Biology, Vanderbilt University Medical Center, 4114 MRB III, Nashville, TN, 37232, USA.
Baojin DingDepartment of Microbiology and Physiological Systems and Program in Neuroscience, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA, 01605-2324, USA.
William B DobynsSeattle Children's Research Institute, Center for Integrative Brain Research, Seattle, WA, USA.
Isabelle DusartSorbonne Universités, Université Pierre et Marie Curie Univ Paris 06, Institut de Biologie Paris Seine, France, 75005, Paris, France.
Parthiv HaldipurSeattle Children's Research Institute, Center for Integrative Brain Research, Seattle, WA, USA.
Mary E HattenLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY, 10065, USA.
Mikio HoshinoDepartment of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo, 187-8502, Japan.
Alexandra L JoynerDevelopmental Biology Program, Sloan Kettering Institute, New York, NY, 10065, USA.
Masanobu KanoDepartment of Neurophysiology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan.
Daniel L KilpatrickDepartment of Microbiology and Physiological Systems and Program in Neuroscience, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA, 01605-2324, USA.
Noriyuki KoibuchiDepartment of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Silvia MarinoBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.
Salvador MartinezDepartment Human Anatomy, IMIB-Arrixaca, University of Murcia, Murcia, Spain.
Kathleen J MillenSeattle Children's Research Institute, Center for Integrative Brain Research, Seattle, WA, USA.
Thomas O MillnerBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.
Takaki MiyataDepartment of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Elena ParmigianiDepartment of Neuroscience Rita Levi Montalcini, University of Turin, via Cherasco 15, 10026, Turin, Italy.
Karl SchillingAnatomie und Zellbiologie, Anatomisches Institut, Rheinische Friedrich-Wilhelms-Universität, Bonn, Germany.
Gabriella SekerkováDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Roy V SillitoeDepartments of Pathology & Immunology and Neuroscience, Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute of Texas Children's Hospital, 1250 Moursund Street, Suite 1325, Houston, TX, 77030, USA.
Constantino SoteloInstitut de la Vision, UPMC Université de Paris 06, Paris, 75012, France.
Naofumi UesakaDepartment of Neurophysiology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan.
Annika WefersCenter for Neuropathology, Ludwig-Maximilians-University, Munich, Germany.
Richard J T WingateMRC Centre for Developmental Neurobiology, King's College London, London, UK.
Richard HawkesDepartment of Cell Biology & Anatomy and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, T2N 4NI, AB, Canada.
Queen Mary University of London · GBSorbonne Université · FRThe University of Tokyo · JPUniversity of Massachusetts Chan Medical School · USUniversity of Turin · ITBaylor College of Medicine · USGunma University · JPKettering University · USKing's College London · GBLudwig-Maximilians-Universität München · DENagoya University · JPNational Center of Neurology and Psychiatry · JPNeurological Research Institute · USNeuroscience Institute · ITNorthwestern University · USRockefeller University · USUniversidad de Murcia · ESUniversity of Bonn · DEUniversity of Calgary · CAUniversity of Oxford · GB
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MThe Genetic Basis of Mid-Hindbrain MalformationsR01NS050375 · NINDS · UNIVERSITY OF MINNESOTA · PI DOBYNS, WILLIAM B. · 2005 to 2019
$9.9MSteps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, SAMACO, RODNEY C · 2014 to 2019
$7.8MEngrailed genes and cerebellum morphology, spatial gene expression and circuitryR37MH085726 · NIMH · SLOAN-KETTERING INST CAN RESEARCH · PI JOYNER, ALEXANDRA L. · 2014 to 2023
$6.7MSignaling Pathways that Regulate Scaling and Regeneration of the CerebellumR01NS092096 · NINDS · SLOAN-KETTERING INST CAN RESEARCH · PI JOYNER, ALEXANDRA L. · 2015 to 2024
$4.8MPathological Mechanisms of Human Cerebeller MalformationsR01NS095733 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI MILLEN, KATHLEEN JOYCE · 2016 to 2020
$3.0MControl of Shh Activity and Signaling in the Neural TubeR01NS042205 · NINDS · VANDERBILT UNIVERSITY · PI CHIANG, CHIN · 2001 to 2013
$2.9MDorsal midline patterning in the vertebrate CNSR01NS072441 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI MILLEN, KATHLEEN JOYCE · 2010 to 2014
$2.3MCongenital brain malformations caused by aberrant head mesenchymal signalingR01NS080390 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI MILLEN, KATHLEEN JOYCE · 2012 to 2016
$2.3MSYNAPTIC ORIGINS OF CEREBELLAR DISEASER01NS089664 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI SILLITOE, ROY VINCENT · 2014 to 2018
$1.7MTemporal Regulation of Neuronal DifferentiationR01NS063047 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KILPATRICK, DANIEL L · 2008 to 2011
$1.3MMedical Research Council G0800020NCI NIH HHS P30 CA008748NICHD NIH HHS U54 HD083092NIMH NIH HHS R37 MH085726NINDS NIH HHS R01 NS042205NINDS NIH HHS R01 NS050375NINDS NIH HHS R01 NS063047NINDS NIH HHS R01 NS072441NINDS NIH HHS R01 NS080390NINDS NIH HHS R01 NS089664NINDS NIH HHS R01 NS092096NINDS NIH HHS R01 NS095733
Abstract
The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and inductive environmental influences. Here, we describe the main processes of cerebellar ontogenesis, highlighting the neurogenic strategies used by developing progenitors, the genetic programs involved in cell fate specification, the progressive changes of structural organization, and some of the better-known abnormalities associated with developmental disorders of the cerebellum.
Indexed as
AnimalsCerebellumHumansNeurogenesisNeuronsCerebellumDifferentiationProgenitorsPurkinje cellsSpecification
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.