ArticlePloS one2015
The Magnitude of Peripheral Muscle Fatigue Induced by High and Low Intensity Single-Joint Exercise Does Not Lead to Central Motor Output Reductions in Resistance Trained Men.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Fatigability of the knee extensors following high- and low-load resistance exercise sessions in trained men.European journal of applied physiology · 2022Trial
- An integrated model of rapid torque production: neuromuscular adaptations under fatigue after strength training.European journal of applied physiology · 2026Article
- Neuromuscular Performance of High-Level Football Goalkeepers by Age Category and Sex: A Systematic Review.Journal of functional morphology and kinesiology · 2025Review
- Low-Intensity Resistance Exercise in Cardiac Rehabilitation: A Narrative Review of Mechanistic Evidence and Clinical Implications.Journal of clinical medicine · 2024Review
- Fatigue, pain, and the recovery of neuromuscular function after consecutive days of full-body resistance exercise in trained men.European journal of applied physiology · 2021Article
- Rate of Force Development as an Indicator of Neuromuscular Fatigue: A Scoping Review.Frontiers in human neuroscience · 2021Article
- Changes in the quadriceps spinal reflex pathway after repeated sprint cycling are not influenced by ischemic preconditioning.European journal of applied physiology · 2020Article
- The effect of IPC on central and peripheral fatiguing mechanisms in humans following maximal single limb isokinetic exercise.Physiological reports · 2019Article
- Trained females exhibit less fatigability than trained males after a heavy knee extensor resistance exercise session.European journal of applied physiology · 2019Article
- Neuromuscular Fatigue at Task Failure and During Immediate Recovery after Isometric Knee Extension Trials.Sports (Basel, Switzerland) · 2018Article
- Reduced Volume 'Daily Max' Training Compared to Higher Volume Periodized Training in Powerlifters Preparing for Competition-A Pilot Study.Sports (Basel, Switzerland) · 2018Article
- Neither load nor systemic hormones determine resistance training-mediated hypertrophy or strength gains in resistance-trained young men.Journal of applied physiology (Bethesda, Md. : 1985) · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine quadriceps muscle fatigue and central motor output during fatiguing single joint exercise at 40% and 80% maximal torque output in resistance trained men.
methodTen resistance trained men performed fatiguing isometric knee extensor exercise at 40% and 80% of maximal torque output. Maximal torque, rate of torque development, and measures of central motor output and peripheral muscle fatigue were recorded at two matched volumes of exercise, and after a final contraction performed to exhaustion. Central motor output was quantified from changes in voluntary activation, normalized surface electromyograms (EMG), and V-waves. Quadriceps muscle fatigue was assessed from changes in the size and shape of the resting potentiated twitch (Q.(pot.tw)). Central motor output during the exercise protocols was estimated from EMG and interpolated twitches applied during the task (VA(sub)).
resultsGreater reductions in maximal torque and rate of torque development were observed during the 40% protocol (p<0.05). Maximal central motor output did not change for either protocol. For the 40% protocol reductions from pre-exercise in rate and amplitude variables calculated from the Q.(pot.tw) between 66.2 to 70.8% (p<0.001) exceeded those observed during the 80% protocol (p<0.01). V-waves only declined during the 80% protocol between 56.8 ± 35.8% to 53.6 ± 37.4% (p<0.05). At the end of the final 80% contraction VA(sub) had increased from 91.2 ± 6.2% to 94.9 ± 4.7% (p = 0.005), but a greater increase was observed during the 40% contraction where VA(sub) had increased from 67.1 ± 6.1% to 88.9 ± 9.6% (p<0.001).
conclusionMaximal central motor output in resistance trained men is well preserved despite varying levels of peripheral muscle fatigue. Upregulated central motor output during the 40% contraction protocol appeared to elicit greater peripheral fatigue. V-waves declines during the 80% protocol suggest intensity dependent modulation of the Ia afferent pathway.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.