ArticleProceedings of the National Academy of Sciences of the United States of America2015
Rapid Y degeneration and dosage compensation in plant sex chromosomes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 1 of them a synthesis that pooled it.
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Who cites it
86 citing papers in PubMed, 1 synthesis or guideline pooled it, 162 citations in OpenAlex.
- Plant sex chromosomes defy evolutionary models of expanding recombination suppression and genetic degeneration.Nature plants · 2021Pooled it
- Developmental robustness of the shoot apical meristem despite sex-chromosome dosage imbalance in Silene latifolia.BMC plant biology · 2026Article
- Silene, a versatile model system: from sex and genome evolution to ecology and speciation.The New phytologist · 2026Review
- An X-linked sex determination mechanism in cannabis and hop.Nature communications · 2026Article
- High-quality genome assembly and linkage map for a rapidly evolving plant species: Silene uniflora.G3 (Bethesda, Md.) · 2026Article
- Recreating viable YYNature communications · 2026Article
- An X-linked sex determination mechanism in cannabis and hop.bioRxiv : the preprint server for biology · 2025Article
- Extensive Recombination Suppression and Genetic Degeneration of a Young ZW Sex Chromosome System in Halfbeak Fish.Molecular biology and evolution · 2025Article
- Effect of heterozygous deletions on phenotypic changes and dosage compensation in Arabidopsis thaliana.Scientific reports · 2025Article
- Hiding in plain sight: the Y chromosome and its reinvigorated role in evolutionary processes.Evolution letters · 2025Article
- TheScience (New York, N.Y.) · 2025Article
- Taxonomic clarification ofPhytoKeys · 2025Article
- ZW sex chromosome structure in Amborella trichopoda.Nature plants · 2024Article
- Random epigenetic inactivation of the X-chromosomal HaMSter gene causes sex ratio distortion in persimmon.Nature plants · 2024Article
- Allopolyploidization from two dioecious ancestors leads to recurrent evolution of sex chromosomes.Nature communications · 2024Article
- Two novel PCR-based assays for sexing ofMethodsX · 2024Article
- Phased Assembly of Neo-Sex Chromosomes Reveals Extensive Y Degeneration and Rapid Genome Evolution in Rumex hastatulus.Molecular biology and evolution · 2024Article
- Evolution of a plant sex chromosome driven by expanding pericentromeric recombination suppression.Scientific reports · 2024Article
- Pericentromeric recombination suppression and the 'large X effect' in plants.Scientific reports · 2023Article
- Evolution of sex-determination in dioecious plants: From active Y to X/A balance?BioEssays : news and reviews in molecular, cellular and developmental biology · 2023Article
26 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The nonrecombining regions of animal Y chromosomes are known to undergo genetic degeneration, but previous work has failed to reveal large-scale gene degeneration on plant Y chromosomes. Here, we uncover rapid and extensive degeneration of Y-linked genes in a plant species, Silene latifolia, that evolved sex chromosomes de novo in the last 10 million years. Previous transcriptome-based studies of this species missed unexpressed, degenerate Y-linked genes. To identify sex-linked genes, regardless of their expression, we sequenced male and female genomes of S. latifolia and integrated the genomic contigs with a high-density genetic map. This revealed that 45% of Y-linked genes are not expressed, and 23% are interrupted by premature stop codons. This contrasts with X-linked genes, in which only 1.3% of genes contained stop codons and 4.3% of genes were not expressed in males. Loss of functional Y-linked genes is partly compensated for by gene-specific up-regulation of X-linked genes. Our results demonstrate that the rate of genetic degeneration of Y-linked genes in S. latifolia is as fast as in animals, and that the evolutionary trajectories of sex chromosomes are similar in the two kingdoms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.