Evidence map›Paper›PMID 26438487›Full record

ArticleAIDS and behavior2016

Accuracy and Acceptability of Oral Fluid HIV Self-Testing in a General Adult Population in Kenya.

Ann E Kurth, Charles M Cleland, Nok Chhun, John E Sidle, Edwin Were, Violet Naanyu, Wilfred Emonyi, Stephen M Macharia, Edwin Sang, Abraham M Siika

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 7 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 7 syntheses or guidelines pooled it, 133 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Article
  17. Article
  18. Observational
  19. Review
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ann E KurthNew York University College of Nursing, 433 First Avenue, 7th Floor, New York, NY, 10003, USA. akurth@nyu.edu.
Charles M ClelandNew York University College of Nursing, 433 First Avenue, 7th Floor, New York, NY, 10003, USA.
Nok ChhunNew York University College of Nursing, 433 First Avenue, 7th Floor, New York, NY, 10003, USA.
John E SidleDepartment of General Internal Medicine, School of Medicine, Indiana University, Indianapolis, IN, USA.
Edwin WereDepartment of Reproductive Health, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
Violet NaanyuDepartment of Behavioral Sciences, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
Wilfred EmonyiDepartment of Immunology, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
Stephen M MachariaMoi Teaching and Referral Hospital, Eldoret, Kenya.
Edwin SangAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Abraham M SiikaDepartment of Medicine, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
AMPATH · KEMoi University · KENew York University · USIndiana University – Purdue University Indianapolis · US

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
NIDA NIH HHS P30 DA011041
6 · The paper itself

Abstract

We evaluated performance, accuracy, and acceptability parameters of unsupervised oral fluid (OF) HIV self-testing (HIVST) in a general population in western Kenya. In a prospective validation design, we enrolled 240 adults to perform rapid OF HIVST and compared results to staff administered OF and rapid fingerstick tests. All reactive, discrepant, and a proportion of negative results were confirmed with lab ELISA. Twenty participants were video-recorded conducting self-testing. All participants completed a staff administered survey before and after HIVST to assess attitudes towards OF HIVST acceptability. HIV prevalence was 14.6 %. Thirty-six of the 239 HIVSTs were invalid (15.1 %; 95 % CI 11.1-20.1 %), with males twice as likely to have invalid results as females. HIVST sensitivity was 89.7 % (95 % CI 73-98 %) and specificity was 98 % (95 % CI 89-99 %). Although sensitivity was somewhat lower than expected, there is clear interest in, and high acceptability (94 %) of OF HIV self-testing.

Indexed as

Self CareAdultAIDS SerodiagnosisFemaleHealth Services AccessibilityHIV AntibodiesHIV InfectionsHIV SeropositivityHumansKenyaMaleMass ScreeningProspective StudiesReagent Kits, DiagnosticSensitivity and SpecificitySurveys and QuestionnairesHIV AntibodiesReagent Kits, DiagnosticHIVOral fluidSelf-testingSensitivitySpecificity

Identifiers

PMID26438487
PMCPMC4799243
OpenAlexW1867571570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.