Evidence map›Paper›PMID 26438486›Full record

ArticleAIDS and behavior2016

Pain and Mortality Risk in a Cohort of HIV-Infected Persons with Alcohol Use Disorders.

Judith I Tsui, Debbie M Cheng, Emily Quinn, Carly Bridden, Jessica S Merlin, Richard Saitz, Jeffrey H Samet

Abstract read
In one paragraph

Article in AIDS and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Judith I TsuiSection of General Internal Medicine, Department of Medicine, University of Washington School of Medicine and Harborview Hospital, 401 Broadway, 5th Floor, Seattle, WA, 98122, USA. tsuij@uw.edu.
Debbie M ChengClinical Addiction Research and Education (CARE) Unit, Section of General Internal Medicine, Department of Medicine, Boston University and Boston Medical Center, Boston, MA, USA.
Emily QuinnData Coordinating Center, Boston University School of Public Health, Boston, MA, USA.
Carly BriddenClinical Addiction Research and Education (CARE) Unit, Section of General Internal Medicine, Department of Medicine, Boston University and Boston Medical Center, Boston, MA, USA.
Jessica S MerlinDivision of Infectious Diseases, University of Alabama School of Medicine, Birmingham, AL, USA.
Richard SaitzClinical Addiction Research and Education (CARE) Unit, Section of General Internal Medicine, Department of Medicine, Boston University and Boston Medical Center, Boston, MA, USA.
Jeffrey H SametClinical Addiction Research and Education (CARE) Unit, Section of General Internal Medicine, Department of Medicine, Boston University and Boston Medical Center, Boston, MA, USA.

Funding

Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Yuhua Bao · 2015 to 2026
$20.7M
Clinical Addiction Research and Education ProgramR25DA013582 · NIDA · BOSTON MEDICAL CENTER · PI JEFFREY H. SAMET, Alexander Yale Walley · 2001 to 2026
$8.9M
CLINICAL IMPACT ON HCV &ALCOHOL IN HIV INFECTED PERSONSR01AA013216 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H · 2000 to 2004
$3.7M
URBAN ARCH (2/5) Biostatistics and Data Management Core (BDM)U24AA020779 · NIAAA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CHENG, DEBBIE M. · 2011 to 2020
$3.6M
URBAN ARCH (1/5) Administrative Coordinating Core (Admin Core)U24AA020778 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2011 to 2020
$3.5M
Development of a Behavioral Intervention for Chronic Pain in Individuals with HIVK23MH104073 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MERLIN, JESSICA S · 2015 to 2018
$732k
HCV and Pain in Substance Users With and Without HIVK23DA027367 · NIDA · BOSTON MEDICAL CENTER · PI TSUI, JUDITH · 2010 to 2013
$651k
NIAAA NIH HHS R01 AA013216NIAAA NIH HHS R01AA013216NIAAA NIH HHS U24 AA020778NIAAA NIH HHS U24AA020778NIAAA NIH HHS U24 AA020779NIAAA NIH HHS U24AA020779NIDA NIH HHS K23 DA027367NIDA NIH HHS K23DA027367NIDA NIH HHS P30 DA040500NIDA NIH HHS R25 DA013582NIDA NIH HHS R25DA013582NIMH NIH HHS K23 MH104073
6 · The paper itself

Abstract

Pain has been associated with increased risk for mortality in some studies. We analyzed data from a cohort study [HIV-longitudinal interrelationships of viruses and ethanol (HIV-LIVE)] of HIV-infected persons with alcohol use disorders enrolled 2001-2003 to explore whether reporting moderate or greater pain interference was associated with mortality. The main independent variable was pain that at least moderately interfered with work based on a single question from the SF-12. Primary analyses dichotomized at "moderately" or above. Cox proportional hazards models assessed the association between pain interference and death adjusting for demographics, substance use, CD4 count, HIV viral load and co-morbidities. Although significant in unadjusted models (HR = 1.58 (95 % CI 1.03-2.41; p value = 0.04)), after adjusting for confounders, ≥moderate pain interference was not associated with an increased risk of death [aHR = 1.30 (95 % CI 0.81-2.11, p value = 0.28)]. Among HIV-infected persons with alcohol use disorders, we did not detect a statistically significant independent association between pain interference and risk of death after adjustment for potential confounders.

Indexed as

MortalityAdultAlcohol DrinkingAlcohol-Related DisordersCD4 Lymphocyte CountCohort StudiesComorbidityHIV InfectionsHumansMaleMiddle AgedPainProportional Hazards ModelsRisk FactorsSocioeconomic FactorsSubstance-Related DisordersHIVMortalityPainSymptoms

Identifiers

PMID26438486
PMCPMC4777650

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.