ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2015
Minimally Invasive Resection of Colorectal Cancer Liver Metastases Leads to an Earlier Initiation of Chemotherapy Compared to Open Surgery.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04163887 (Effect of the Laparoscopic Approach in Reducing Postoperative Severe Complications Following Hepatectomy for Colorectal Liver Metastases), which is not on this map. Cited by 30 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of the Laparoscopic Approach in Reducing Postoperative Severe Complications Following Hepatectomy for Colorectal Liver Metastases: Prospective, Randomized, Controlled Study
Who cites it
30 citing papers in PubMed, 5 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Short-Term Outcomes After Robotic Versus Open Liver Resection: A Systematic Review and Meta-analysis.Journal of gastrointestinal cancer · 2023Pooled it
- Laparoscopic versus open liver resection for hepatocellular carcinoma in elderly patients: A systematic review and meta-analysis of propensity score-matched studies.Frontiers in oncology · 2022Pooled it
- [Evidence of minimally invasive oncological surgery of the liver].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Pooled it
- A systematic review and meta-analysis comparing the short- and long-term outcomes for laparoscopic and open liver resections for liver metastases from colorectal cancer.Surgical endoscopy · 2020Pooled it
- Laparoscopic Versus Open Liver Resection for Colorectal Liver Metastases: A Comprehensive Systematic Review and Meta-analysis.Scientific reports · 2017Pooled it
- Open versus minimally invasive liver surgery for colorectal liver metastases (LapOpHuva): a prospective randomized controlled trial.Surgical endoscopy · 2019Trial
- Robotic liver surgery: enhancing immune competence and minimizing postsurgical inflammation.Surgical endoscopy · 2025Article
- "Winning" with laparoscopic liver resection for colorectal cancer liver metastases (CRLM).Hepatobiliary surgery and nutrition · 2025Article
- Evolution of minimally invasive liver surgery in France over the last decade.Surgical endoscopy · 2024Article
- Review
- Review
- Advances in minimally invasive liver surgery.Northern clinics of Istanbul · 2024Review
- Outcomes and Patient Selection in Laparoscopic vs. Open Liver Resection for HCC and Colorectal Cancer Liver Metastasis.Cancers · 2023Review
- Recent Advances in Minimally Invasive Liver Resection for Colorectal Cancer Liver Metastases-A Review.Cancers · 2022Review
- Laparoscopic liver resection for colorectal liver metastases - short- and long-term outcomes: A systematic review.World journal of gastrointestinal oncology · 2021Article
- Predictive ability of preoperative CT scan for the intraoperative difficulty and postoperative outcomes of laparoscopic liver resection.Surgical endoscopy · 2021Article
- Is minimally invasive surgery of lesions in the right superior segments of the liver justified? A multi-institutional study of 245 patients.Journal of surgical oncology · 2020Article
- Integrative Concepts for Liver Surgery.Visceral medicine · 2020Review
- Current status of laparoscopic liver resection for the management of colorectal liver metastases.Journal of gastrointestinal oncology · 2020Review
- Timing of Perioperative Chemotherapy Does Not Influence Long-Term Outcome of Patients Undergoing Combined Laparoscopic Colorectal and Liver Resection in Selected Upfront Resectable Synchronous Liver Metastases.World journal of surgery · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
introductionPrevious studies have shown benefit not only from postoperative chemotherapy but also from a short interval to initiation of treatment after resection of primary colorectal cancer. The aim of this study was to determine difference in timing to postoperative chemotherapy for minimally invasive resection (MIR) vs. open resection (OR) of colorectal cancer liver metastases (CRCLM).
methodsThis is a retrospective review of 1:1 matched patients undergoing MIR (n = 66) and OR (n = 66) for CRCLM at a single institution.
resultsPatients undergoing MIR of CRCLM had significantly shorter length of hospital stay, fewer major complications, and shorter interval to postoperative chemotherapy (median 42 vs. 63 days, p < 0.001). Univariable analysis showed that surgical approach, postoperative complications, blood loss, number of lesions, and length of stay were associated with timing to chemotherapy. On multivariable analysis, surgical approach was still associated with timing to chemotherapy, and postoperative complications resulted in a delay of chemotherapy among patients who underwent OR but not among those who underwent MIR. In addition, worse disease-free survival was seen among patients who received postoperative chemotherapy more than 60 days after surgery.
conclusionBy modifying the deleterious effects of postoperative complications on timing of postoperative chemotherapy, patients undergoing MIR for CRCLM are treated with chemotherapy sooner after surgery compared to those undergoing OR.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.