Evidence map›Paper›PMID 26438468›Full record

ArticleAmerican journal of men's health2018

Changes in Depression Subtypes Among Men in STAR*D: A Latent Transition Analysis.

Christine M Ulbricht, Levent Dumenci, Anthony J Rothschild, Kate L Lapane

Open access · bronzeAbstract readComparative StudyMulticenter Study
In one paragraph

Article in American journal of men's health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Motor abnormalities, depression risk, and clinical course in adolescence.Biological psychiatry global open science · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Christine M Ulbricht1 University of Massachusetts Medical School, Worcester, MA, USA.
Levent Dumenci2 Temple University College of Public Health, Philadelphia, PA, USA.
Anthony J Rothschild1 University of Massachusetts Medical School, Worcester, MA, USA.
Kate L Lapane1 University of Massachusetts Medical School, Worcester, MA, USA.
University of Massachusetts Chan Medical School · USTemple University · USUMass Memorial Health Care · US

Funding

Acute Pharmacotherapy of Unipolar Psychotic DepressionU01MH062624 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ROTHSCHILD, ANTHONY J · 2002 to 2015
$2.9M
Development of an Instrument to Measure Health Literacy in Cancer PatientsR01CA140151 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI DUMENCI, LEVENT · 2010 to 2013
$2.2M
In-hospital Antipsychotic Use among Elderly Patients Discharged to Nursing HomesR21AG046839 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LAPANE, KATE L · 2014 to 2015
$454k
NCI NIH HHS R01 CA140151NHLBI NIH HHS HHSN268201000020CNIA NIH HHS R21 AG046839NIMH NIH HHS U01 MH062624
6 · The paper itself

Abstract

The burden of depression in men is high. Current diagnostic criteria may not fully capture men's experience with depression. Descriptions of the heterogeneity in depression among men are lacking. The purpose of the study was to characterize latent subtypes of major depression and changes in these subtypes among men receiving citalopram in Level 1 of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial. Latent transition analysis was applied to data from 387 men who completed baseline and Week 12 study visits in Level 1 of STAR*D. Items from the self-report version of the Quick Inventory of Depressive Symptomatology were used as indicators of latent depression subtypes. Four statuses were identified at baseline and Week 12. Baseline statuses were Mild (10% of men), Moderate (53%), Severe with Psychomotor Slowing (20%), and Severe with Psychomotor Agitation (17%). At Week 12, the statuses were Symptom Resolution (41%), Mild (36%), Moderate (18%), and Severe with Psychomotor Slowing (5%). Men in the Mild status were most likely to transition to Symptom Resolution (probability = 69%). Men in the Severe with Agitation status were least likely to transition to Symptom Resolution (probability = 0%). This work highlights the need to not focus solely on summary rating scores but to also consider patterns of symptoms when treating depression.

Indexed as

Patient Reported Outcome MeasuresAdultAge FactorsAntidepressive Agents, Second-GenerationCitalopramCohort StudiesHealth SurveysHumansIncidenceMajor Depressive DisorderMaleMen's HealthNeuropsychological TestsPatient SelectionPrognosisPsychiatric Status Rating ScalesAntidepressive Agents, Second-GenerationCitalopramdepression subtypeslatent transition analysismajor depressive disorderSTAR*D

Identifiers

PMID26438468
PMCPMC5734533
OpenAlexW2310253494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.