Evidence map›Paper›PMID 26438309›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2016

Non-hip and non-vertebral fractures: the neglected fracture sites.

K L Holloway, M J Henry, S L Brennan-Olsen, G Bucki-Smith, G C Nicholson, S Korn, K M Sanders, J A Pasco, M A Kotowicz

Abstract read
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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Clinical utility of one-third radius BMD in a population-based prospective cohort of older adults: Insights from the São Paulo Aging & Health (SPAH) study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  2. Article
  3. Article
  4. Costs of incident non-hip osteoporosis-related fractures in postmenopausal women from a payer perspective.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Article
  5. Article
  6. Incidence and risk factors for osteoporotic non-vertebral fracture in low-income community-dwelling elderly: a population-based prospective cohort study in Brazil. The São Paulo Ageing and Health (SPAH) study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  7. Article
  8. New anabolic therapies for osteoporosis.Internal and emergency medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

K L HollowayEpi-Centre for Healthy Ageing (ECHA), IMPACT Strategic Research Centre, Kitchener House (Barwon Health), PO Box 281, Geelong, VIC, 3220, Australia. khollo@barwonhealth.org.au.
M J HenryBarwon Health, Ryrie Street, Geelong, VIC, Australia.
S L Brennan-OlsenEpi-Centre for Healthy Ageing (ECHA), IMPACT Strategic Research Centre, Kitchener House (Barwon Health), PO Box 281, Geelong, VIC, 3220, Australia.
G Bucki-SmithEpi-Centre for Healthy Ageing (ECHA), IMPACT Strategic Research Centre, Kitchener House (Barwon Health), PO Box 281, Geelong, VIC, 3220, Australia.
G C NicholsonThe Institute for Health and Ageing, Australian Catholic University, Melbourne, VIC, Australia.
S KornBarwon Health, Ryrie Street, Geelong, VIC, Australia.
K M SandersThe Institute for Health and Ageing, Australian Catholic University, Melbourne, VIC, Australia.
J A PascoEpi-Centre for Healthy Ageing (ECHA), IMPACT Strategic Research Centre, Kitchener House (Barwon Health), PO Box 281, Geelong, VIC, 3220, Australia.
M A KotowiczEpi-Centre for Healthy Ageing (ECHA), IMPACT Strategic Research Centre, Kitchener House (Barwon Health), PO Box 281, Geelong, VIC, 3220, Australia.
Barwon Health · AUUniversity of Melbourne · AUAustralian Catholic University · AUUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryNon-hip, non-vertebral fractures (NHNVF) were compared with hip, vertebral and controls. NHNVF were younger and heavier than controls and hip/vertebral fractures in both men and women, respectively. Falls and prior fractures were less common in NHNVF than hip fractures. Glucocorticoid use was lower in NHNVF compared to vertebral fracture (VF) in men.

introductionAlthough hip fracture (HF) and vertebral fractures (VF) receive the most attention in the literature and are the targeted sites for fracture prevention, non-hip, non-vertebral fracture (NHNVF) sites account for a greater proportion of fractures than the hip or vertebrae. This study aimed to assess risk factors for NHNVF and compare them with those for HF, VF and controls.

methodsIncident fractures during 2005-2007 for men and 1994-1996 for women were identified using computerised keyword searches of radiological reports, and controls were selected at random from electoral rolls for participation in the Geelong Osteoporosis Study. Participants aged 60+ years were included in this study.

resultsCompared to controls, men and women with NHNVF were younger (ORs, 0.90, 95% CI 0.86-0.94; and 0.96, 0.93-0.98, respectively) and had a lower femoral neck bone mineral density (BMD) T-score (age-adjusted; difference [men] 0.383, P = 0.002; [women] 0.287, P = 0.001). Compared to HF, men and women with NHNVF were heavier (difference [men] 9.0 kg, P = 0.01; [women] 7.6 kg, P < 0.001). Heavier weight was also a risk factor for women with NHNVF compared to VF (1.03, 1.01-1.06). In men with NHNVF, falls (0.37, 0.14-0.97) and prior fractures (0.38, 0.15-0.98) were less common compared to HF; and glucocorticoid use was less common for NHNVF (0.30, 0.11-0.85) compared to VF.

conclusionsGiven the high numbers of NHNVF sustained by men and women in this study, fracture prevention strategies should focus on individuals with high risk of sustaining these types of fractures, as well as on individuals who are more likely to sustain a HF or VF.

Indexed as

Accidental FallsAgedAged, 80 and overAge FactorsBody WeightBone DensityCase-Control StudiesFemaleFemur NeckGlucocorticoidsHip FracturesHumansMaleMiddle AgedOsteoporotic FracturesRisk FactorsGlucocorticoidsElderlyFracturesNon-hipNon-vertebral fracturesRisk factors

Identifiers

PMID26438309
OpenAlexW2230089972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.