Evidence map›Paper›PMID 26438224›Full record

GuidelineIntensive care medicine2015

Task force on management and prevention of Acinetobacter baumannii infections in the ICU.

José Garnacho-Montero, George Dimopoulos, Garyphallia Poulakou, Murat Akova, José Miguel Cisneros, Jan De Waele, Nicola Petrosillo, Harald Seifert, Jean François Timsit, Jordi Vila and 3 more

Abstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 3 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 174 citations in OpenAlex.

  1. Data-driven Atlas ofFrontiers in cellular and infection microbiology · 2026
    Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Carbapenem-resistantMicrobiology spectrum · 2026
    Article
  6. Article
  7. Comparative genomic insights into carbapenem-resistant versus susceptibleFrontiers in cellular and infection microbiology · 2026
    Article
  8. Article
  9. JAC-antimicrobial resistance · 2025
    Article
  10. Turning the Tide Against Carbapenem-resistantOpen forum infectious diseases · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Multidrug-ResistantTropical medicine and infectious disease · 2025
    Article
  16. The intricacies ofFrontiers in microbiology · 2025
    Review
  17. Multidrug resistantCurrent research in microbial sciences · 2025
    Review
  18. Review
  19. Review
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 7 countries.

José Garnacho-MonteroUnidad Clínica de Cuidados Intensivos, Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío, Seville, Spain. jgarnachom@gmail.com.
George DimopoulosDepartment of Critical Care, University Hospital ATTIKON, Medical School, University of Athens, Athens, Greece.
Garyphallia Poulakou4th Department of Internal Medicine, Athens University School of Medicine, Attikon University General Hospital, Athens, Greece.
Murat AkovaDepartment of Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey.
José Miguel CisnerosUnidad Clínicia de Enfermedades Infecciosas, Microbiología y Preventiva, Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío, Seville, Spain.
Jan De WaeleDepartment of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Nicola Petrosillo2nd Infectious Disease Division, National Institute for Infectious Diseases 'L. Spallanzani', Rome, Italy.
Harald SeifertInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Jean François TimsitMedical and Infectious Diseases ICU, Bichat Hospital, 75018, Paris, France.
Jordi VilaDepartment of Clinical Microbiology, CDB, Hospital Clínic, School of Medicine, University of Barcelona, Centre for International Health Research, (CRESIB-Hospital Clínic), Barcelona, Spain.
Jean-Ralph ZaharUnité de Prévention et de Lutte Contre les Infections Nosocomiales, Université d'Angers, Centre Hospitalo-universitaire d'Angers, Angers, France.
Matteo BassettiInfectious Diseases Clinic, Santa Maria Misericordia University Hospital, Udine, Italy.
European Society of Intensive Care Medicine
Ghent University Hospital · BEHacettepe University · TRHôpital Bichat-Claude-Bernard · FRHospital Universitario Virgen del Rocío · ESNational and Kapodistrian University of Athens · GROspedale Santa Maria della Misericordia di Udine · ITUniversitat de Barcelona · ESUniversity General Hospital Attikon · GRUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcinetobacter baumannii constitutes a dreadful problem in many ICUs worldwide. The very limited therapeutic options available for these organisms are a matter of great concern. No specific guidelines exist addressing the prevention and management of A. baumannii infections in the critical care setting.

methodsClinical microbiologists, infectious disease specialists and intensive care physicians were invited by the Chair of the Infection Section of the ESICM to participate in a multidisciplinary expert panel. After the selection of clinically relevant questions, this document provides recommendations about the use of microbiological techniques for identification of A. baumannii in clinical laboratories, antibiotic therapy for severe infections and recommendations to control this pathogen in outbreaks and endemic situations. Evidence supporting each statement was graded according to the European Society of Clinical Microbiology and Infection Diseases (ESCMID) grading system.

resultsEmpirical coverage of A. baumannii is recommended in severe infections (severe sepsis or septic shock) occurring during an A. baumannii outbreak, in an endemic setting, or in a previously colonized patient. For these cases, a polymyxin is suggested as part of the empirical treatment in cases of a high suspicion of a carbapenem-resistant (CR) A. baumannii strain. An institutional program including staff education, promotion of hand hygiene, strict contact and isolation precautions, environmental cleaning, targeted active surveillance, and antimicrobial stewardship should be instituted and maintained to combat outbreaks and endemic situations.

conclusionsSpecific recommendations about prevention and management of A. baumannii infections in the ICU were elaborated by this multidisciplinary panel. The paucity of randomized controlled trials is noteworthy, so these recommendations are mainly based on observational studies and pharmacodynamics modeling.

Indexed as

Acinetobacter baumanniiIntensive Care UnitsAcinetobacter InfectionsAnti-Bacterial AgentsCross InfectionDecision TreesDisease OutbreaksHumansAnti-Bacterial AgentsAcinetobacter baumanniiColistinEpidemiologyPreventionTreatment

Identifiers

PMID26438224
OpenAlexW1823347141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.