ArticleScientific reports2015
Phylum-wide analysis of genes/proteins related to the last steps of assembly and export of extracellular polymeric substances (EPS) in cyanobacteria.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 97 citations in OpenAlex.
- Role of Cyanobacterial Exopolysaccharide in Soil Fertility: Composition, Mechanism and Application.Current microbiology · 2026Review
- Transfer of the synechan biosynthesis and regulatory pathway enables sulfated polysaccharide production in Synechococcus elongatus PCC 7942.Scientific reports · 2026Article
- Genetic engineering to improve resistance against heavy metal stress inApplied and environmental microbiology · 2026Article
- Interactions between phytoplankton and bacterioplankton communities in Caohai plateau lake, revealed by environmental DNA metagenomics.BMC microbiology · 2026Article
- Insights into biosynthesis, regulation, and functional potentials of exopolysaccharide from Leptolyngbya sp. MKU-05.World journal of microbiology & biotechnology · 2025Article
- Towards the control of biofilm formation in Anabaena (Nostoc) sp. PCC7120: novel insights into the genes involved and their regulation.The New phytologist · 2025Article
- Biofilm Formation, Modulation, and Transcriptomic Regulation Under Stress Conditions inInternational journal of molecular sciences · 2025Article
- Article
- Application of Nanomaterials in the Production of Biomolecules in Microalgae: A Review.Marine drugs · 2023Review
- Cellulose Synthase in Atacama Cyanobacteria and Bioethanol Production from Their Exopolysaccharides.Microorganisms · 2023Article
- Environmental modulation of exopolysaccharide production in the cyanobacterium Synechocystis 6803.Applied microbiology and biotechnology · 2023Article
- Novel diversity of polar Cyanobacteria revealed by genome-resolved metagenomics.Microbial genomics · 2023Article
- Article
- Metagenomic, (bio)chemical, and microscopic analyses reveal the potential for the cycling of sulfated EPS in Shark Bay pustular mats.ISME communications · 2022Article
- CRISPRi as a Tool to Repress Multiple Copies of Extracellular Polymeric Substances (EPS)-Related Genes in the CyanobacteriumLife (Basel, Switzerland) · 2021Article
- Biosynthesis of a sulfated exopolysaccharide, synechan, and bloom formation in the model cyanobacteriumeLife · 2021Article
- Disentangling the Impact of Sulfur Limitation on Exopolysaccharide and Functionality of Alr2882 by In Silico Approaches in Anabaena sp. PCC 7120.Applied biochemistry and biotechnology · 2021Article
- Environmentally relevant concentrations of titanium dioxide nanoparticles pose negligible risk to marine microbes.Environmental science. Nano · 2021Article
- Biotechnological Production of the Sunscreen Pigment Scytonemin in Cyanobacteria: Progress and Strategy.Marine drugs · 2021Review
- Absence of KpsM (Slr0977) Impairs the Secretion of Extracellular Polymeric Substances (EPS) and Impacts Carbon Fluxes inmSphere · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many cyanobacteria produce extracellular polymeric substances (EPS) with particular characteristics (e.g. anionic nature and presence of sulfate) that make them suitable for industrial processes such as bioremediation of heavy metals or thickening, suspending or emulsifying agents. Nevertheless, their biosynthetic pathway(s) are still largely unknown, limiting their utilization. In this work, a phylum-wide analysis of genes/proteins putatively involved in the assembly and export of EPS in cyanobacteria was performed. Our results demonstrated that most strains harbor genes encoding proteins related to the three main pathways: Wzy-, ABC transporter-, and Synthase-dependent, but often not the complete set defining one pathway. Multiple gene copies are mainly correlated to larger genomes, and the strains with reduced genomes (e.g. the clade of marine unicellular Synechococcus and Prochlorococcus), seem to have lost most of the EPS-related genes. Overall, the distribution of the different genes/proteins within the cyanobacteria phylum raises the hypothesis that cyanobacterial EPS production may not strictly follow one of the pathways previously characterized. Moreover, for the proteins involved in EPS polymerization, amino acid patterns were defined and validated constituting a novel and robust tool to identify proteins with similar functions and giving a first insight to which polymer biosynthesis they are related to.
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