Evidence map›Paper›PMID 26437729›Full record

ArticleAustralian and New Zealand journal of public health2015

Cancers in Australia in 2010 attributable to and prevented by the use of combined oral contraceptives.

Susan J Jordan, Louise F Wilson, Christina M Nagle, Adele C Green, Catherine M Olsen, Christopher J Bain, Nirmala Pandeya, David C Whiteman, Penelope M Webb

Abstract read
In one paragraph

Article in Australian and New Zealand journal of public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Breast Cancer in Australian Indigenous Women: Incidence, Mortality, and Risk FactorsAsian Pacific journal of cancer prevention : APJCP · 2017
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Susan J JordanQIMR Berghofer Medical Research Institute, Queensland.
Louise F WilsonQIMR Berghofer Medical Research Institute, Queensland.
Christina M NagleQIMR Berghofer Medical Research Institute, Queensland.
Adele C GreenQIMR Berghofer Medical Research Institute, Queensland.
Catherine M OlsenQIMR Berghofer Medical Research Institute, Queensland.
Christopher J BainQIMR Berghofer Medical Research Institute, Queensland.
Nirmala PandeyaQIMR Berghofer Medical Research Institute, Queensland.
David C WhitemanQIMR Berghofer Medical Research Institute, Queensland.
Penelope M WebbQIMR Berghofer Medical Research Institute, Queensland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate the proportion and number of cancers occurring in Australia in 2010 attributable to combined oral contraceptive pill (OCP) use.

methodsWe estimated the population attributable fraction (PAF) for cancers causally associated with combined OCP use (breast, cervix), and the proportion of endometrial and ovarian cancers prevented (prevented fraction [PF]). We used standard formulae incorporating prevalence of combined OCP use in the Australian population, relative risks of cancer associated with this exposure and cancer incidence.

resultsAn estimated 105 breast and 52 cervical cancers (0.7% and 6.4% of each cancer, respectively) in Australia in 2010 were attributable to current use of combined OCP. Past combined OCP use was estimated to have prevented 1,032 endometrial and 308 ovarian cancers in 2010, reducing the number of cancers that would otherwise have occurred by 31% and 19%, respectively.

conclusionsA small proportion of breast and cervical cancers is attributable to combined OCP use; OCP use is likely to have prevented larger numbers of endometrial and ovarian cancers. IMPLICATIONS: Women seeking contraceptive advice should be told of potential adverse effects, but should also be told that - along with reproductive health benefits - combined OCP use can reduce long-term risks of ovarian and endometrial cancers.

Indexed as

AdolescentAdultAgedAustraliaBreast NeoplasmsContraceptives, Oral, CombinedEndometrial NeoplasmsFemaleHumansIncidenceMiddle AgedOvarian NeoplasmsPopulation SurveillanceRiskUterine Cervical NeoplasmsYoung AdultContraceptives, Oral, Combinedcancerinfectionpopulation attributable fractionrisk factor

Identifiers

PMID26437729
PMCPMC4606778

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.