Evidence map›Paper›PMID 26437592›Full record

ArticleTrends in cell biology2015

Beyond the Linear Genome: Paired-End Sequencing as a Biophysical Tool.

Viviana I Risca, William J Greenleaf

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Viviana I RiscaDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, 94305, USA.
William J GreenleafDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, 94305, USA; Department of Applied Physics, Stanford University, Stanford, CA, 94305, USA. Electronic address: wjg@stanford.edu.

Funding

VACCINE INDUCED IMMUNITY IN THE YOUNG AND AGEDU19AI057266 · NIAID · EMORY UNIVERSITY · PI Rafi Ahmed · 2003 to 2026
$81.7M
Special EquipmentP50HG007735 · NHGRI · STANFORD UNIVERSITY · PI CHANG, HOWARD Y · 2014 to 2018
$15.2M
Genomics of Gene Regulation in Progenitor to Differentiated KeratinocytesU01HG007919 · NHGRI · STANFORD UNIVERSITY · PI SNYDER, MICHAEL P. · 2015 to 2017
$7.0M
Mapping chromatin secondary structure by sequencing correlated DNA strand breaksR21HG007726 · NHGRI · STANFORD UNIVERSITY · PI GREENLEAF, WILLIAM JAMES · 2014 to 2015
$441k
NHGRI NIH HHS P50 HG007735NHGRI NIH HHS P50HG007735NHGRI NIH HHS R21 HG007726NHGRI NIH HHS R21HG007726NHGRI NIH HHS U01 HG007919NHGRI NIH HHS U01HG007919NIAID NIH HHS U19 AI057266NIAID NIH HHS U1AI057266
6 · The paper itself

Abstract

Paired-end sequencing has enabled a variety of new methods for high-throughput interrogation of both genome structure and chromatin architecture. Here, we discuss how the paired-end paradigm can be used to interpret sequencing data as biophysical measurements of in vivo chromatin structure that report on single molecules in single cells.

Indexed as

AnimalsBiophysical PhenomenaChromosome MappingGenomeHumansSequence Analysis, DNAchromatinchromosome structurein vivo measurementspaired-end sequencing

Identifiers

PMID26437592
PMCPMC5540433

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.