ArticleScientific reports2015
Antimicrobial activity of iron oxide nanoparticle upon modulation of nanoparticle-bacteria interface.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 171 papers, 1 of them a synthesis that pooled it.
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Who cites it
171 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metal Nanoparticles in Infection and Immunity.Immunological investigations · 2020Pooled it
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- In Vitro antibacterial, anti-biofilm, and virulence-modulating activity of Cinnamomum verum-mediated iron oxide nanoparticles against carbapenem-resistant uropathogenic Escherichia coli.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Fabrication of nitrofurantoin-loaded chitosan-silver nanoparticles for the treatment of urinary tract infections.Scientific reports · 2026Article
- Formulation-Dependent Antibacterial Performance: Design and Biomedical Applications.Gels (Basel, Switzerland) · 2026Review
- Magnetic Field-Driven Strategies for Biofilm Disruption: From Iron Oxide Nanoparticles to Adaptive Swarms of Magnetic Microrobots.ACS nano · 2026Review
- LPS-focused nanomedicine for potent antibacterial therapy.Nanomedicine (London, England) · 2025Review
- Shaping Magnetic Hyperthermia Properties through Nanoparticle Surface-Ligand Design: Implications for Cellular Responses.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
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- Surface modifications of graphitic carbon nitride with metal particles and polymer blend as antibacterial and dye removal agents.Scientific reports · 2025Article
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- Engineering Nanomaterials for Raman Bioimaging and Theranostics: Advances, Challenges, and Future Directions.ACS omega · 2025Review
- Surface modifications of superparamagnetic iron oxide nanoparticles with citric acid, selenium, and silver combining with polymer blend as antibacterial agent.Discover nano · 2025Article
- Ultrasound- and NIR-Responsive Polydextran/Black TiOACS applied materials & interfaces · 2025Article
- In vitro experimental study of MC-PMMA containing vancomycin for the prevention of infection in open bone defects.Journal of materials science. Materials in medicine · 2025Article
- Magnetite-Assisted Capture Affinity, Concentration Dependence, and Magnetic Extraction Rate ofMicroorganisms · 2025Article
- Fabrication and application of naturally sourced nano-pigments based on algal biomass in multifunctional coatings.Scientific reports · 2025Article
111 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Investigating the interaction patterns at nano-bio interface is a key challenge for safe use of nanoparticles (NPs) to any biological system. The study intends to explore the role of interaction pattern at the iron oxide nanoparticle (IONP)-bacteria interface affecting antimicrobial propensity of IONP. To this end, IONP with magnetite like atomic arrangement and negative surface potential (n-IONP) was synthesized by co-precipitation method. Positively charged chitosan molecule coating was used to reverse the surface potential of n-IONP, i.e. positive surface potential IONP (p-IONP). The comparative data from fourier transform infrared spectroscope, XRD, and zeta potential analyzer indicated the successful coating of IONP surface with chitosan molecule. Additionally, the nanocrystals obtained were found to have spherical size with 10-20 nm diameter. The BacLight fluorescence assay, bacterial growth kinetic and colony forming unit studies indicated that n-IONP (<50 μM) has insignificant antimicrobial activity against Bacillus subtilis and Escherichia coli. However, coating with chitosan molecule resulted significant increase in antimicrobial propensity of IONP. Additionally, the assay to study reactive oxygen species (ROS) indicated relatively higher ROS production upon p-IONP treatment of the bacteria. The data, altogether, indicated that the chitosan coating of IONP result in interface that enhances ROS production, hence the antimicrobial activity.
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