ArticlePLoS neglected tropical diseases2015
Urban Market Gardening and Rodent-Borne Pathogenic Leptospira in Arid Zones: A Case Study in Niamey, Niger.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- A systematic review and meta-analysis ofOne health (Amsterdam, Netherlands) · 2026Review
- Molecular detection of a Leptospira lineage with high similarity to Leptospira kirschneri in human, environmental, and rodent samples from Gilan Province, Iran: an integrated field and laboratory investigation.GMS hygiene and infection control · 2026Article
- Review
- Review
- Detection of two zoonotic pathogens,One health (Amsterdam, Netherlands) · 2025Article
- Helminthofauna Diversity in Synanthropic Rodents of the Emilia-Romagna Region (Italy): Implications for Public Health and Rodent Control.Veterinary sciences · 2024Article
- Molecular surveillance of zoonotic pathogens from wild rodents in the Republic of Korea.PLoS neglected tropical diseases · 2024Article
- Spatiotemporal assessment of pathogenicJournal of water and health · 2024Article
- Leptospirosis Cases among Outpatients with Non-Malaria Fever Attending Primary Care Clinics during the Rainy Season in Bobo Dioulasso, Burkina Faso.The American journal of tropical medicine and hygiene · 2024Article
- Article
- First Molecular Detection of PathogensTropical medicine and infectious disease · 2022Article
- Fine-scale prevalence and genetic diversity of urban small mammal-borne pathogenic Leptospira in Africa: A spatiotemporal survey within Cotonou, Benin.Zoonoses and public health · 2022Article
- Ecology and distribution of Leptospira spp., reservoir hosts and environmental interaction in Sri Lanka, with identification of a new strain.PLoS neglected tropical diseases · 2022Article
- Article
- Molecular Detection of Microorganisms Associated with Small Mammals and Their Ectoparasites in Mali.The American journal of tropical medicine and hygiene · 2020Article
- Rodents as Hosts of Pathogens and Related Zoonotic Disease Risk.Pathogens (Basel, Switzerland) · 2020Article
- Environmental DNA metabarcoding to detect pathogenic Leptospira and associated organisms in leptospirosis-endemic areas of Japan.Scientific reports · 2019Article
- Systematic Review of Important Bacterial Zoonoses in Africa in the Last Decade in Light of the 'One Health' Concept.Pathogens (Basel, Switzerland) · 2019Review
- Association of rodent-borne Leptospira spp. with urban environments in Malaysian Borneo.PLoS neglected tropical diseases · 2019Article
- BRC4Env, a network of Biological Resource Centres for research in environmental and agricultural sciences.Environmental science and pollution research international · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 4 countries.
Funding
Abstract
Leptospirosis essentially affects human following contact with rodent urine-contaminated water. As such, it was mainly found associated with rice culture, recreational activities and flooding. This is also the reason why it has mainly been investigated in temperate as well as warm and humid regions, while arid zones have been only very occasionally monitored for this disease. In particular, data for West African countries are extremely scarce. Here, we took advantage of an extensive survey of urban rodents in Niamey, Niger, in order to look for rodent-borne pathogenic Leptospira species presence and distribution across the city. To do so, we used high throughput bacterial 16S-based metabarcoding, lipL32 gene-targeting RT-PCR, rrs gene sequencing and VNTR typing as well as GIS-based multivariate spatial analysis. Our results show that leptospires seem absent from the core city where usual Leptospira reservoir rodent species (namely R. rattus and M. natalensis) are yet abundant. On the contrary, L. kirschneri was detected in Arvicanthis niloticus and Cricetomys gambianus, two rodent species that are restricted to irrigated cultures within the city. Moreover, the VNTR profiles showed that rodent-borne leptospires in Niamey belong to previously undescribed serovars. Altogether, our study points towards the importance of market gardening in maintain and circulation of leptospirosis within Sahelian cities. In Africa, irrigated urban agriculture constitutes a pivotal source of food supply, especially in the context of the ongoing extensive urbanization of the continent. With this in mind, we speculate that leptospirosis may represent a zoonotic disease of concern also in arid regions that would deserve to be more rigorously surveyed, especially in urban agricultural settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.