Evidence map›Paper›PMID 26437430›Full record

ReviewGenes2015

Impact of Chromatin on HIV Replication.

Luis M Agosto, Matthew Gagne, Andrew J Henderson

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Delivering CRISPR to the HIV-1 reservoirs.Frontiers in microbiology · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. A functional screen identifies transcriptional networks that regulate HIV-1 and HIV-2.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. CD4AIDS research and human retroviruses · 2018
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Luis M AgostoDepartment of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. agosto@bu.edu.
Matthew GagneGraduate Program in Microbiology, Boston University School of Medicine, Boston, MA 02118, USA. patsfan@bu.edu.
Andrew J HendersonDepartment of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. andrew.henderson@bmc.org.
Boston University · US

Funding

RESEARCH TRAINING IN IMMUNOLOGYT32AI007309 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GUMMULURU, SURYARAM · 1988 to 2024
$7.4M
Transcription mechanisms that contribute to HIV-1 latencyR01AI097117 · NIAID · BOSTON MEDICAL CENTER · PI HENDERSON, ANDREW J · 2013 to 2016
$1.7M
Oral Macrophage Function in the Context of Periodontal Disease and HIV InfectionR56DE023950 · NIDCR · BOSTON MEDICAL CENTER · PI GIBSON, FRANK C, HENDERSON, ANDREW J · 2013 to 2014
$1.1M
Novel compounds that target HIV latencyR21AI108447 · NIAID · BOSTON MEDICAL CENTER · PI HENDERSON, ANDREW J · 2014 to 2015
$488k
Transcriptional mechanisms that contribute to HIV-1 latencyR56AI097117 · NIAID · BOSTON MEDICAL CENTER · PI HENDERSON, ANDREW J · 2011 to 2011
$433k
NIAID NIH HHS R01 AI097117NIAID NIH HHS R21 AI108447NIAID NIH HHS R56 AI097117NIAID NIH HHS T32 AI007309NIDCR NIH HHS R56 DE023950
6 · The paper itself

Abstract

Chromatin influences Human Immunodeficiency Virus (HIV) integration and replication. This review highlights critical host factors that influence chromatin structure and organization and that also impact HIV integration, transcriptional regulation and latency. Furthermore, recent attempts to target chromatin associated factors to reduce the HIV proviral load are discussed.

Indexed as

chromatinHIVintegrationlatencytranscription

Identifiers

PMID26437430
PMCPMC4690024
OpenAlexW2159367056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.