Evidence map›Paper›PMID 26437296›Full record

ArticleJournal of the mechanical behavior of biomedical materials2016

A mechanical argument for the differential performance of coronary artery grafts.

David A Prim, Boran Zhou, Adam Hartstone-Rose, Mark J Uline, Tarek Shazly, John F Eberth

Abstract read
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Hemodynamics and Wall Mechanics of Vascular Graft Failure.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Longitudinal histomechanical heterogeneity of the internal thoracic artery.Journal of the mechanical behavior of biomedical materials · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Tissue engineering. Part C, Methods · 2019
    Article
  12. Article
  13. Article
  14. Coaxially-structured fibres with tailored material properties for vascular graft implant.Materials science & engineering. C, Materials for biological applications · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David A PrimUniversity of South Carolina, Biomedical Engineering Program, Columbia, SC, USA.
Boran ZhouUniversity of South Carolina, Biomedical Engineering Program, Columbia, SC, USA.
Adam Hartstone-RoseUniversity of South Carolina School of Medicine, Department of Cell Biology and Anatomy, Columbia, SC, USA; University of South Carolina, Department of Anthropology, Columbia, SC, USA.
Mark J UlineUniversity of South Carolina, Biomedical Engineering Program, Columbia, SC, USA; University of South Carolina, Department of Chemical Engineering, Columbia, SC, USA.
Tarek ShazlyUniversity of South Carolina, Biomedical Engineering Program, Columbia, SC, USA; University of South Carolina, Department of Mechanical Engineering, Columbia, SC, USA.
John F EberthUniversity of South Carolina, Biomedical Engineering Program, Columbia, SC, USA; University of South Carolina School of Medicine, Department of Cell Biology and Anatomy, Columbia, SC, USA. Electronic address: John.Eberth@uscmed.sc.edu.

Funding

South Carolina IDeA Networks of Biomedical Research (SC INBRE V)P20GM103499 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI EDIE C GOLDSMITH · 2012 to 2026
$61.0M
NIGMS NIH HHS P20 GM103499NIGMS NIH HHS P20GM103499
6 · The paper itself

Abstract

Coronary artery bypass grafting (CABG) acutely disturbs the homeostatic state of the transplanted vessel making retention of graft patency dependent on chronic remodeling processes. The time course and extent to which remodeling restores vessel homeostasis will depend, in part, on the nature and magnitude of the mechanical disturbances induced upon transplantation. In this investigation, biaxial mechanical testing and histology were performed on the porcine left anterior descending artery (LAD) and analogs of common autografts, including the internal thoracic artery (ITA), radial artery (RA), great saphenous vein (GSV) and lateral saphenous vein (LSV). Experimental data were used to quantify the parameters of a structure-based constitutive model enabling prediction of the acute vessel mechanical response pre-transplantation and under coronary loading conditions. A novel metric Ξ was developed to quantify mechanical differences between each graft vessel in situ and the LAD in situ, while a second metric Ω compares the graft vessels in situ to their state under coronary loading. The relative values of these metrics among candidate autograft sources are consistent with vessel-specific variations in CABG clinical success rates with the ITA as the superior and GSV the inferior graft choices based on mechanical performance. This approach can be used to evaluate other candidate tissues for grafting or to aid in the development of synthetic and tissue engineered alternatives.

Indexed as

Coronary VesselsMechanical PhenomenaAnimalsBiomechanical PhenomenaHomeostasisMaterials TestingStress, MechanicalSwineBypass graftCABGMechanical compatibilityStress homeostasis

Identifiers

PMID26437296
PMCPMC4921230

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.