Observational studyPediatric pulmonology2015
Adherence to airway clearance therapy in pediatric cystic fibrosis: Socioeconomic factors and respiratory outcomes.
Observational study in Pediatric pulmonology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cross-Cutting mHealth Behavior Change Techniques to Support Treatment Adherence and Self-Management of Complex Medical Conditions: Systematic Review.JMIR mHealth and uHealth · 2024Pooled it
- Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis.The Cochrane database of systematic reviews · 2023Pooled it
- Adherence and barriers to hyperinsufflation in children with congenital muscular dystrophy.Pediatric pulmonology · 2017Trial
- Associations Between Socioeconomic Status and Adherence to Medications in People With Cystic Fibrosis.Pediatric pulmonology · 2025Article
- Impact of sociodemographic status and sex on chronic rhinosinusitis and olfaction in people with cystic fibrosis.International forum of allergy & rhinology · 2024Article
- Impact of intrinsic and extrinsic risk factors on early-onset lung disease in cystic fibrosis.Pediatric pulmonology · 2023Article
- Aiming to Improve Equity in Pulmonary Health: Cystic Fibrosis.Clinics in chest medicine · 2023Review
- Socioeconomic determinants of respiratory health in patients with cystic fibrosis: implications for treatment strategies.Expert review of respiratory medicine · 2022Review
- Association between insurance variability and early lung function in children with cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022Observational
- Telehealth use in cystic fibrosis during COVID-19: Association with race, ethnicity, and socioeconomic factors.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2021Article
- Social Inequities and Cystic Fibrosis Outcomes: We Can Do Better.Annals of the American Thoracic Society · 2021Article
- Tobacco smoke exposure and socioeconomic factors are independent predictors of pulmonary decline in pediatric cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2020Article
- The demographics of adverse outcomes in cystic fibrosis.Pediatric pulmonology · 2019Review
- Objective Versus Self-Reported Adherence to Airway Clearance Therapy in Cystic Fibrosis.Respiratory care · 2019Article
- Developing Digital Games to Address Airway Clearance Therapy in Children With Cystic Fibrosis: Participatory Design Process.JMIR serious games · 2018Article
- Article
- Outcome evaluation of a pharmacy-based therapy management program for patients with cystic fibrosis.Pediatric pulmonology · 2018Observational
- Article
- Socioeconomic Status, Smoke Exposure, and Health Outcomes in Young Children With Cystic Fibrosis.Pediatrics · 2017Article
- Patient knowledge and pulmonary medication adherence in adult patients with cystic fibrosis.Patient preference and adherence · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectivesThe evidence linking socioeconomic status (SES) and adherence in cystic fibrosis (CF) is inconclusive and focused on medication uptake. We examined associations between SES, adherence to airway clearance therapy (ACT), and CF respiratory outcomes. STUDY
designSocioeconomic, clinical, and adherence data of CF patients (N = 110) at a single CF Center were evaluated in this cross-sectional observational study. SES was operationalized as maternal and paternal education and household income. Adherence to ACT was measured with utilization data from the high-frequency chest wall oscillation (HFCWO) device over 4-6 weeks. Statistical modeling was used to test three hypotheses: (H1) Higher SES is associated with higher ACT adherence; (H2) Higher SES is associated with better respiratory outcomes; and (H3) ACT adherence mediates the relationship between SES and respiratory outcomes.
resultsIn multinomial logistic regression, maternal college education, annual income >$50,000, and more adults in the household were independently related to better adherence (P < 0.05). Paternal college education, income >$100,000, and lack of exposure to smoking were independently related to higher lung function (P < 0.05). Current adherence to ACT with HFCWO was not associated with lung function over 12 months.
conclusionsSES is associated both with ACT adherence and respiratory outcomes in pediatric CF patients. However, the link between SES and respiratory outcomes in this study was not mediated by adherence to ACT with HFCWO. These data emphasize the importance of socioeconomic resources and household environment for CF health. Family socio-demographic profiles can help identify patients at increased risk for ACT nonadherence.
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