Evidence map›Paper›PMID 26435843›Full record

ArticleGlobal mental health (Cambridge, England)2015

Improving mental health among people living with HIV: a review of intervention trials in low- and middle-income countries.

Kathleen J Sikkema, Alexis C Dennis, Melissa H Watt, Karmel W Choi, Tatenda T Yemeke, John A Joska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global mental health (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 6 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kathleen J SikkemaDuke University, Department of Psychology and Neuroscience, Durham, NC ; Duke Global Health Institute, Durham, NC.
Alexis C DennisDuke Global Health Institute, Durham, NC.
Melissa H WattDuke Global Health Institute, Durham, NC.
Karmel W ChoiDuke University, Department of Psychology and Neuroscience, Durham, NC ; Duke Global Health Institute, Durham, NC.
Tatenda T YemekeDuke Global Health Institute, Durham, NC.
John A JoskaUniversity of Cape Town, Department of Psychiatry and Mental Health, Cape Town, South Africa.

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Improving the health of South African women with traumatic stress in HIV careR34MH102001 · NIMH · DUKE UNIVERSITY · PI SIKKEMA, KATHLEEN J · 2014 to 2016
$581k
NIAID NIH HHS P30 AI064518NIMH NIH HHS R34 MH102001
6 · The paper itself

Abstract

People living with HIV (PLWH) experience greater psychological distress than the general population. Evidence from high-incomes countries suggests that psychological interventions for PLWH can improve mental health symptoms, quality of life, and HIV care engagement. However, little is known about the effectiveness of mental health interventions for PLWH in low and middle-income countries (LMICs), where the large majority of PLWH reside. This systematized review aims to synthesize findings from mental health intervention trials with PLWH in LMICs to inform the delivery of mental health services in these settings. A systematic search strategy was undertaken to identify peer-reviewed published papers of intervention trials addressing negative psychological states or disorders (e.g., depression, anxiety) among PLWH in LMIC settings. Search results were assessed against pre-established inclusion and exclusion criteria. Data from papers meeting criteria were extracted for synthesis. Twenty-six papers, published between 2000 and 2014, describing 22 unique interventions were identified. Trials were implemented in sub-Saharan Africa (n=13), Asia (n=7), and the Middle East (n=2), and addressed mental health using a variety of approaches, including cognitive-behavioral (n=18), family-level (n=2), and pharmacological (n=2) treatments. Four randomized controlled trials reported significant intervention effects in mental health outcomes, and eleven preliminary studies demonstrated promising findings. Among the limited mental health intervention trials with PLWH in LMICs, few demonstrated efficacy. Mental health interventions for PLWH in LMICs must be further developed and adapted for resource-limited settings to improve effectiveness.

Indexed as

HIVinterventionlow middle income countriesmental healthreviewtrials

Identifiers

PMID26435843
PMCPMC4589870

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.