Evidence map›Paper›PMID 26435777›Full record

ReviewWorld journal of radiology2015

Radiation signature on exposed cells: Relevance in dose estimation.

Venkatachalam Perumal, Tamizh Selvan Gnana Sekaran, Venkateswarlu Raavi, Safa Abdul Syed Basheerudeen, Karthik Kanagaraj, Amith Roy Chowdhury, Solomon Fd Paul

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Venkatachalam PerumalVenkatachalam Perumal, Tamizh Selvan Gnana Sekaran, Venkateswarlu Raavi, Safa Abdul Syed Basheerudeen, Karthik Kanagaraj, Amith Roy Chowdhury, Solomon FD Paul, Department of Human Genetics, College of Biomedical Sciences, Technology and Research, Sri Ramachandra University, Porur, Chennai 600 116, India.
Tamizh Selvan Gnana SekaranVenkatachalam Perumal, Tamizh Selvan Gnana Sekaran, Venkateswarlu Raavi, Safa Abdul Syed Basheerudeen, Karthik Kanagaraj, Amith Roy Chowdhury, Solomon FD Paul, Department of Human Genetics, College of Biomedical Sciences, Technology and Research, Sri Ramachandra University, Porur, Chennai 600 116, India.
Venkateswarlu RaaviVenkatachalam Perumal, Tamizh Selvan Gnana Sekaran, Venkateswarlu Raavi, Safa Abdul Syed Basheerudeen, Karthik Kanagaraj, Amith Roy Chowdhury, Solomon FD Paul, Department of Human Genetics, College of Biomedical Sciences, Technology and Research, Sri Ramachandra University, Porur, Chennai 600 116, India.
Safa Abdul Syed BasheerudeenVenkatachalam Perumal, Tamizh Selvan Gnana Sekaran, Venkateswarlu Raavi, Safa Abdul Syed Basheerudeen, Karthik Kanagaraj, Amith Roy Chowdhury, Solomon FD Paul, Department of Human Genetics, College of Biomedical Sciences, Technology and Research, Sri Ramachandra University, Porur, Chennai 600 116, India.
Karthik KanagarajVenkatachalam Perumal, Tamizh Selvan Gnana Sekaran, Venkateswarlu Raavi, Safa Abdul Syed Basheerudeen, Karthik Kanagaraj, Amith Roy Chowdhury, Solomon FD Paul, Department of Human Genetics, College of Biomedical Sciences, Technology and Research, Sri Ramachandra University, Porur, Chennai 600 116, India.
Amith Roy ChowdhuryVenkatachalam Perumal, Tamizh Selvan Gnana Sekaran, Venkateswarlu Raavi, Safa Abdul Syed Basheerudeen, Karthik Kanagaraj, Amith Roy Chowdhury, Solomon FD Paul, Department of Human Genetics, College of Biomedical Sciences, Technology and Research, Sri Ramachandra University, Porur, Chennai 600 116, India.
Solomon Fd PaulVenkatachalam Perumal, Tamizh Selvan Gnana Sekaran, Venkateswarlu Raavi, Safa Abdul Syed Basheerudeen, Karthik Kanagaraj, Amith Roy Chowdhury, Solomon FD Paul, Department of Human Genetics, College of Biomedical Sciences, Technology and Research, Sri Ramachandra University, Porur, Chennai 600 116, India.
Sri Ramachandra Institute of Higher Education and Research · INCreative Research Enterprises (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The radiation is considered as a double edged sword, as its beneficial and detrimental effects have been demonstrated. The potential benefits are being exploited to its maximum by adopting safe handling of radionuclide stipulated by the regulatory agencies. While the occupational workers are monitored by personnel monitoring devices, for general publics, it is not a regular practice. However, it can be achieved by using biomarkers with a potential for the radiation triage and medical management. An ideal biomarker to adopt in those situations should be rapid, specific, sensitive, reproducible, and able to categorize the nature of exposure and could provide a reliable dose estimation irrespective of the time of the exposures. Since cytogenetic markers shown to have many advantages relatively than other markers, the origins of various chromosomal abnormalities induced by ionizing radiations along with dose-response curves generated in the laboratory are presented. Current status of the gold standard dicentric chromosome assay, micronucleus assay, translocation measurement by fluorescence in-situ hybridization and an emerging protein marker the γ-H2AX assay are discussed with our laboratory data. With the wide choice of methods, an appropriate assay can be employed based on the net.

Indexed as

BiomarkerDicentric chromosomesFluorescence in-situ hybridizationMicronucleus

Identifiers

PMID26435777
PMCPMC4585950
OpenAlexW2407114052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.